“MyoD is not powerful because it commands other genes from above. It is powerful because its position in the regulatory network is such that its presence or absence reshapes the entire downstream landscape. Adding it to a fibroblast doesn’t just flip a switch; it reorganizes what the cell is." 💡
Nivedita Sarveswaran
Our latest review is out. We take a deep dive into the human mutations in microtubule motors that drive devastating neurodevelopmental and neurodegenerative diseases. Taking in motor protein biophysics, animal models of disease as well as patient phenotypes.
onlinelibrary.wiley.com/doi/full/10....
Having been someone calling for UKRI to give the community greater notice on call deadlines, I welcome this.
Drawing on the kids primary school feedback mechanism, here some feedback on today's announcement:
🧵
🚀 Exciting opportunity for early career researchers in Cell & Developmental Biology!
🔗 Learn more and apply: www.ucl.ac.uk/life-science...
Please share with your networks or tag someone who should apply! 👇
“We have enjoyed strong cross-party support for R&D, but we can’t assume that’s going to continue. If the public aren’t seeing the value when there are difficult choices to be made with public finances, I think that’s a real threat,” Welham told @isaacbarbosa1.bsky.social
Full piece here:
According to @edvardmoser.bsky.social, director of the Kavli Institute for Systems Neuroscience, the four recipients of the Kavli Prize in Neuroscience challenged what had long been regarded as a central dogma in neuroscience.
By Alissa de Chassey
www.thetransmitter.org/awards/four-...
Check out the paper in @stemcellreports.bsky.social
www.cell.com/stem-cell-re...
A collaborative effort between researchers at @fraunhoferitmp.bsky.social, @eu-openscreen.bsky.social, @mdc-berlin.bsky.social, and @hhu.de
UCL Research Department of Cell & Developmental Biology
Kirsty Grainger
Emily R. Trunnell, Ph.D.
Robin Bisson
10 colour palettes I reach for in research charts — curated, and most are colourblind-safe. Categorical + sequential: Okabe-Ito, Paul Tol, Tableau 10, viridis, cividis, magma.
Skip default tab10 and rainbow/jet.
Which do you swear by? Anything I'm missing?
#DataViz #ColorPalette #SciComm
The Transmitter
Ted Price
www.researchprofessionalnews.com
New Royal Society of Biology president raises concern that “political buy-in could weaken”
/PRNewswire/ -- 4E Therapeutics, Inc. ("4E"), an Austin-based neuroscience company developing next-generation treatments for chronic pain, today announced that...
We’ve launched a new space on our website to help you explore upcoming UKRI funding opportunities.
The page gives a longer-term view of more than 45 opportunities opening between now and December.
Explore the page: www.ukri.org/apply-for-fu...
www.ucl.ac.uk
We are now inviting expressions of interest from early career researchers who wish to be sponsored for external fellowships to establish an independent research group in CDB.
@thetransmitter.bsky.social asked what scientific paper has impacted me most. Hal Weintraub's discovery that MyoD alone can convert naive cells into muscle cells seemed like magic. I've been chasing that kind of magic ever since: www.thetransmitter.org/this-paper-c...
Wittich et al. provide an overview of human PSC-derived organoid screening technologies
and outline key considerations for integrating them into drug discovery pipelines.
As new approach methodologies...
Many women may not be using the best pain relief for period cramps, a big study of supermarket receipts suggests.
Paracetamol/acetaminophen was most commonly bought with tampons & sanitary towels, but Ibuprofen/Advil more effectively deals with muscle cramps. 🧪💊
www.bbc.co.uk/news/article...