How does a DNA repair enzyme find a needle in a haystack? 🧬
Our latest paper in NAR, led by the one and only C-trap queen Kaitlin Dehart, uses single-molecule imaging to watch APE1 scan DNA and lock onto AP-sites. @lumicks.bsky.social
academic.oup.com/nar/article/...
Abstract. Apurinic/apyrimidinic (AP) sites are among the most frequent DNA lesions, arising thousands of times per cell each day. These lesions threaten ge
