Professor studying the interplay between DNA damage and human health. WY➡️CSU➡️UI➡️NIEHS➡️KU. Personal posts from science to society.
Bret Freudenthal
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Save the date: the 26th Annual Midwest DNA Repair Symposium heads to Indiana, June 4 to 6, 2027. See you there.
I am honored to receive a 2026 University Scholarly Achievement Award from KU. They say it takes a village. Mine took a village and then some: my lab, my trainees, my family. The award has my name on it, but it is theirs. They do they hard work and make this the best job ever!🙏 youtu.be/o-KcgX3IiP8
Huge thanks also to the team that made this video and captured the lab so well, the colleagues and collaborators who shaped how I do science, and the KU Cancer Center and KUMC for building a place that values people and mentorship. @kucancercenter.bsky.social @universityofkansas.bsky.social
How does a DNA repair enzyme find a needle in a haystack? 🧬
Our latest paper in NAR, led by the one and only C-trap queen Kaitlin Dehart, uses single-molecule imaging to watch APE1 scan DNA and lock onto AP-sites. @lumicks.bsky.social
academic.oup.com/nar/article/...
Our keynote speakers gave inspiring talks, and the trainees absolutely hit it out of the park. We were proud to hand out 17 trainee awards (nearly $8,000 in travel/awards).
And none of it happens without my co-organizer Ryan Barnes and members of the Freudenthal and Barnes labs who kept everything running smoothly. Couldn't have done it without you. Thank you also to our 14 sponsors for making it all possible, particularly the NIEHS and KUCC.
www.biorxiv.org/content/10.6...
New research space for the group: RNA binding proteins!
Been chipping away at this for about 3 years now. But, pretty cool to see how a single PTM in an IDR changes overall configurational states of ordered domains.
That's a wrap on the 25th Annual Midwest DNA Repair Symposium at the University of Kansas Medical Center. Two days, 175 attendees, 4 keynotes, 22 talks, and 85 posters of genuinely incredible science (also some fun socializing of course). I am still smiling, but a bit tired. 🧬🌻
Abstract. Apurinic/apyrimidinic (AP) sites are among the most frequent DNA lesions, arising thousands of times per cell each day. These lesions threaten ge
But the people made it. Supportive, generous, and kind in that unmistakably Midwestern way. While it is currently a challenging moment for academic science in America, it was a much needed reminder of why I love this work: the people, the science, and the trainees.
Bret Freudenthal
A season of change in the lab.
🎓 Hooding ceremony for Spencer Thompson who is headed back to the clinic.
🧬 Zach Onyszchuk joins the lab as a graduate student
🔬 Nicholas @nicholaswashton.bsky.social joins the lab as Senior Scientist
Excited for what's ahead!!
