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A mild strategy compatible with various solvents, air, and moisture @angewandtechemie.bsky.social Congratulations to all involved! Geminal Difunctionalization of Ketones via C─S Bond Insertion of Photogenerated Donor–Donor Diazo Compounds doi.org/10.1002/anie...

From donor/core CV to catalyst design: a new method to develop inexpensive and tunable organic RL/NIR photocatalysts. Dual Ni/photoredox C–heteroatom coupling with a new cyanoarene photocatalyst under 620 nm LEDs! @angewandtechemie.bsky.social #Chemsky #photocatalysis doi.org/10.1002/anie...

Electrochemistry enables sustainable access to phosphorylated amine libraries from natural feedstocks, yielding bioisosteric analogues of amino acid derivatives. Congrats to the team! #ChemSky #electrochemistry doi.org/10.1039/D6QO...

We broadened the scope of 4-isoxazolines and oxa-aza-BCHeps in a highly regioselective fashion by photocontrol over strain and topology. A template for designing next-generation therapeutics and agrochemicals! Congrats to the team! doi.org/10.26434/che...

Our combination of metal- and photocatalysis enables the selective synthesis of aniline under mild conditions and allows easy scaling with flow systems. Nice team work! #ChemSky #photocatalysis doi.org/10.1002/chem...

'On Water' hydrogen bonding stabilizes the photo-excited state of quinones: application of Franck-Condon principle in organic synthesis. Congrats to all! #ChemSky #photocatalysis doi.org/10.1038/s414... “On-water” photosensitization enables redox neutral acylation and alkylation of quinones

Our perspective charts the potential of water as a programmable reaction medium using compatible catalysts, EDA complexes, engineered micelles and microdroplets. Aqueous-phase organic photochemistry: Distinct modes and interfaces #ChemSky #photochemistry #watersoluble doi.org/10.1016/j.ch...

We used industrially preferred solvents, base, and low catalyst loadings to offer a significant advancement in the practicality and scalability of industrial processes. Another collaboration with Bayer! pubs.acs.org/doi/10.1021/...

We thank B. List and L. Alama for highlighting our collaboration pubs.acs.org/doi/10.1021/... in Synfacts! #ChemSky #photocatalysis Synthesis of α-Amino Acids via ConPET-Driven Amide Activation doi.org/10.1055/a-27...

Three-dimensional, conformationally rigid molecular architectures are increasingly valued in chemical biology, and drug discovery, yet their syntheses often rely on step-intensive or metal-mediated methods. Herein, we report a metal-free, redox-neutral ...

Geminal difunctionalization of readily available building blocks provides rapid access to molecular complexity. This work introduces a strategy for installing two distinct functional groups on a carb...

Given the widespread use of organophosphorus scaffolds in several disciplines, the formation of C(sp3)–P bonds is of fundamental importance. Direct access to α-phosphorylated amines still remains chal...

Photochemical activation of N-phenylphenothiazine (PPT) enables a selective direct benzene amination with hydroxylamine in the presence of various vanadium catalysts under mild reaction conditions. S...

From redox numbers to red light: Donor oxidation and core reduction potentials predict E0-0 in cyanoarene dyes, guiding selection of an efficient red-light catalyst, 4MeODPATPN (PC13). Under 620 nm l...

Water-oil interfaces exhibit high cohesive energy density and form a supramolecular hydrogen-bonding network, which supports organic reactions in various ways. Here, the authors introduce the redox-ne...

We present a novel copper-catalyzed method for aniline cross-couplings promoted by a 6-hydroxy picolinhydrazide ligand. The method achieves room-temperature reactivity with aryl bromides, enabled by a methanol/ethanol solvent mixture and a mild, functional group-compatible base, with catalyst loadings as low as 0.5 mol %. The use of industrially preferred solvents and base, as well as the high catalytic activity, offers a significant advancement in the practicality and scalability of industrial processes. Furthermore, the approach extends to the cross-coupling of aryl chlorides under elevated temperatures and demonstrates compatibility with additional nucleophile classes.

New Editor’s Choice collection ➡ 𝐎𝐫𝐠𝐚𝐧𝐢𝐜 𝐂𝐡𝐞𝐦𝐢𝐬𝐭𝐫𝐲 𝐢𝐧 𝐆𝐫𝐞𝐞𝐧 𝐂𝐡𝐞𝐦𝐢𝐬𝐭𝐫𝐲: 𝐊𝐞𝐲 𝐇𝐢𝐠𝐡𝐥𝐢𝐠𝐡𝐭𝐬 🔗 rsc.li/GCOrganic Outstanding research in organic chemistry that showcases advances in green chemistry. 🆓 Free to access until end of July 2026 #GreenChemistry #OrganicChemistry @rsc.org