Three days, fresh data, & sparkly debates on how replication gaps drive cancer & disease. Grateful for every talk & discussion. Thank you for pushing science forward—next stop: great papers. Science moves fast when we move together!
The Expanding Roles of Homologous Recombination Proteins in Genome Stability
@labvincenzo.bsky.social review how RAD51 shields DNA from nucleolytic processing, promotes fork reversal, suppresses replicative DNA gaps, binds abasic sites to avert cytotoxic conversion
link.springer.com/article/10.1...
Come and join us to celebrate the 10th anniversary of the BCGB, with a great selection of international speakers! Very convenient conference, open to anyone interested in the field of genome biology!
Another great science appointment is coming up with @labvincenzo.bsky.social and @luijsterburglab.bsky.social! 🧬
🗓️ Join us live on Tuesday, June 9th at 5pm (Rome) / 11am (NYC).
📍 Zoom link: uzh.zoom.us/j/6598481621...
📥 Register here to stay in the loop: docs.google.com/forms/d/e/1F...
www.sciencedirect.com/science/arti...
Pleased to share our paper. We found surprising widespread glycogen accumulation in A-T due to mitochondrial
impairment that can be improved by targeting the unexpected FNIP2-SERCA2b-axis.
#AtaxiaTelangiectasia #ATM #RareDisease #Metabolism #Mitochondria
www.nature.com/articles/s41...
Excited to share our new review in Molecular Cell on replicative single-stranded DNA gaps and their role in genome instability and cancer therapy.
#DNARepair #ReplicationStress #GenomeStability #CancerResearch #MolecularBiology #PARPinhibitors
www.cell.com/molecular-ce...
This work wouldn't have been possible without @angelotaglialatela.bsky.social, Jen-Wei Huang, @giuseppeleuzzi.bsky.social, and members of the labs of @traver.bsky.social, Raphael Guerois, @labvincenzo.bsky.social, Raul Rabadan, @nussenza.bsky.social, @jenscs83.bsky.social, @heyzajr.bsky.social.