🇨🇦 boiling in the Arizona desert and not riding my bikes enough. Cancer researcher focused on multiple myeloma and clinical genomics at TGen, part of City of Hope. Creator of MyelomaSky and Sequencing Tech feeds. Director, Collaborative Sequencing Center
Jonathan Keats, PhD 🇨🇦
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In case you missed it: last night, CBS News awarded the Mike Wallace Memorial Scholarship to Santiago Campos, a high school journalist. In accepting, he took the time to condemn the direction of CBS News to much surprise and applause from the audience.
This is a very big deal, awesome work!
Video
Sounds like something worth a read
Charlotte Clymer
William "Chip" Nagel
Jonathan Keats, PhD 🇨🇦
Jonathan Keats, PhD 🇨🇦
If you want to know what 3′UTRs with long conserved sequence stretches do, check out our BioRxiv preprint doi.org/10.64898/202....
They form functional intermolecular 3′UTR-3′UTR interactions that enable co-folding of proteins to rapidly induce transcriptional programs.
Christine Mayr
A new paper reports identification of a binder of IRF4 and development of a selective degrader that exhibits strong cytotoxicity against multiple myeloma cell lines
www.nature.com/articles/s41...
Identification of a binder of interferon regulatory factor 4 (IRF4) enabled development of a selective degrader, dIRF4-2, that exhibited strong cytotoxicity in multiple myeloma cell lines, offering an...
