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Finally, Hunter Hill used In(1)w^m4 (one of the original X-chroms from Muller's 1930 paper) to show Wolbachia acts as a variegation suppressor. Wolbachia-mediated modification of paternal chromatin during spermatogenesis leaves a persistent signature on heterochromatin-mediated silencing. Very cool
#2 Led by Basabi Bagchi and Dylan Shropshire assesses temperature modulation of cytoplasmic incompatibility strength across 8 systems. With the help of Lore, Tim (Phd), and Elena/Kyle (undergrads), we show cifB expression partly explains temp-sensitive CI, while bacterial density in testes does not.
Excited to share this preprint!! with @brandonscooper.bsky.social and Bill Sullivan We tested whether endosymbiotic Wolbachia can alter host gene expression through chromatin modifications that persist from spermatogenesis to adulthood.
Wolbachia-induced cytoplasmic incompatibility produces heritable chromatin modifications that suppress position-effect variegation https://www.biorxiv.org/content/10.64898/2026.06.12.731975v1