Finally, Hunter Hill used In(1)w^m4 (one of the original X-chroms from Muller's 1930 paper) to show Wolbachia acts as a variegation suppressor. Wolbachia-mediated modification of paternal chromatin during spermatogenesis leaves a persistent signature on heterochromatin-mediated silencing. Very cool
Maternally transmitted Wolbachia often cause cytoplasmic incompatibility (CI), a sperm modification that kills host embryos lacking the endosymbiont. CI produces defects in paternal chromosome replica...
