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Scientist interested in #integrons, antimicrobial resistance and the molecular basis of adaptation. Working at at CNB-CSIC.
Jose A Escudero









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Bacteria have been fighting off viruses using a huge arsenal of molecular weaponry that scientists did not know about — until now. Researchers have identified proteins that could lead to virus-fighting drugs and technologies. go.nature.com/4dqQnXI
2mo
Interesting, and sequencing-based. "These findings definitively point to the ancestral origin of the Columbus lineage within the noble houses of Northern Spain, specifically the Zúñiga (Navarre) and Sotomayor (Galicia) families" Do you reckon this will settle things? www.biorxiv.org/content/10.6...
New preprint alert!!! 🚀🤓 We are very happy to finally share this with the world — the result of seven years of work and a new tool to study integrons and discover new functions encoded in these bacterial platforms. If you want to know more, here is a thread 🧵 www.biorxiv.org/content/10.6...
"Tell me who your friends are, and I’ll tell you who you are." It turns out, microbes follow the same rule! Very proud to share our lab's new paper in @natmicrobiol.nature.com showing that bacteria don't just respond to their environment, they respond to each other. www.nature.com/articles/s41...
1mo
Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.
‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools
go.nature.com
2mo
1mo
En #AGolpeDeBit #RTVE, @sanmillan.bsky.social investigador del #CNB @csic.es habla de este estudio liderado junto a Alfonso Santos López @uam.es y en colaboración con Ayari Fuentes #UNAM_MX centrado en el plásmido pOXA-48 de gran interés clínico 📻 ¡No te lo pierdas! www.rtve.es/play/audios/...
The United States now has the most government restrictions on academic freedom of any high-income country. www.chemistryworld.com/news/academi... Raw data from @vdeminstitute.bsky.social —> academic-freedom-index.net/research/Aca...
How diverse is bacterial immunity ? We report in @science.org how language models allowed us to predict 2.4M antiphage proteins spanning >23K novel potential systems. 👏 @emordret.bsky.social, @alexhv.bsky.social & al doi.org/10.1126/scie... Explore them here defensefinder.mdmlab.fr/wiki/refseq_...
www.biorxiv.org
Nature
2mo
www.biorxiv.org
A big advance in the field of bacterial immunity, from the Bernheim and Laub labs
1mo
2mo
Biotic interactions modulate protein abundance, reducing functional redundancy and increasing productivity in complex bacterial communities.
www.nature.com
Community context reshapes microbial proteomes and reduces functional overlap - Nature Microbiology
Jose A Escudero
Cool tool to capture genes using a hunter gatherer 🦠 Large-scale recovery of integron cassettes for gene discovery screens www.biorxiv.org/content/10.6... by @jaescudero.bsky.social @afpcarvalho.bsky.social @filipatr.bsky.social
2mo
Ponemos el foco en un estudio que identifica un nuevo mecanismo por el que los plásmidos pueden acelerar la aparición de resistencia a los antibióticos
www.rtve.es
Resistencia a antibióticos: hallada nueva clave en plásmidos
www.science.org
2mo
Mizrahi Lab
Filipa Trigo da Roza
Aude Bernheim
Centro Nacional de Biotecnología (CNB)
Michael Clemens
Bacteria have been fighting off viruses using a huge arsenal of molecular weaponry that scientists did not know about — until now. Researchers have identified proteins that could lead to virus-fighting drugs and technologies. go.nature.com/4dqQnXI
2mo
Sorek Lab
Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.
‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools
go.nature.com
Zeynep Baharoglu
Nature
Check out Snorre's latest preprint: www.biorxiv.org/content/10.6... I love this story: our 4-species synthetic bacterial community coexists across many simple environments and conditions. We show why (spoiler in the title)
1mo
www.biorxiv.org
Sara Mitri
Happy to finally share these results: Cross-feeding enables robust coexistence between four bacterial species www.biorxiv.org/content/10.6... With @saramitri.bsky.social @lambdapp.bsky.social @dan1elmachado.bsky.social @lhtxra.bsky.social Eric Ulrich, Alisson Gillon & Sam Testa #microsky
1mo
Snorre Sulheim