Very interesting paper from Susan Hamilton's lab, showing that phosphorylation of RyR1 by SPEG kinase can suppress pathological consequences of disease mutations.
www.science.org/doi/10.1126/...
Reducing Ca2+ leak through mutant RYR1 prevents pathological heat production in skeletal muscle.
A pity for the field that 8+ years have passed between publication and retraction, or even the several years after the first concerns were raised. Kudos to Schrag and coworkers to keep pushing for honest science!
Citation nonsense.
Our paper on Ryanodine Receptor disease mutations gets cited in a paper about nanocellulose...
advanced.onlinelibrary.wiley.com/doi/full/10....
Journals could use an AI tool to weed through irrelevant citations. Or is this entire paper an AI hallucination?