Developmental Biology Lab focused on normal and malignant hematopoiesis. We employ synthetic biology to tackle fundamental biological and medical questions.
https://www.ganuzalab.org
Barts Cancer Institute, QMUL @qmbci.bsky.social
Ganuza Lab
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www.nature.com/articles/s41...
📢 Check out our article in its final format in @natcomms.nature.com
Unbiased recording of thymic cellular interactomes via synthetic Notch receptors
#synNotch #Tcells #thymus #syntheticbiology
@qmbci.bsky.social
Explore the March #ExpHem Issue now with articles from Atsushi Iwama, Jian Xu, Momoko Yoshimoto, @ganuzalab.bsky.social and many more ➡️ www.exphem.org/issue/S0301-...
journals.lww.com/co-hematolog...
Check our Review article on the emerging roles of BEACH Domain Containing Proteins in hematopoiesis and immune homeostasis published in Current Opinion in Hematology
onlinelibrary.wiley.com/doi/10.1111/...
Thrilled to share our work in BJH highlighting the therapeutic potential of targeting the WNT pathway to block the crosstalk among stromal and leukemic ALL cells to prevent chemoresistance.
Collab. w/ Bela Wrench
@foteinikal.bsky.social
@qmbci.bsky.social
Special congratulations to Raúl Sánchez-Lanzas (first author) and all the Team:
@miajpompa.bsky.social
@qmbci.bsky.social
#syntheticNotchReceptors
#cell-to-cell-contact-invivo-recording
#syntheticBiology
www.nature.com/articles/s41...
Extremely proud of our publication in @natcomms.nature.com.
We report a genetic system based on synthetic Notch receptors (Yin&Yang) that we engineered to record and identify cell-to-cell interactions in vivo in the thymus.
Collaboration @mirjana-efremova.bsky.social
Explore the February #ExpHem issue, with articles from the labs of Jean-Pierre Lévesque, @ganuzalab.bsky.social, Katrin Ottersbach, Duonan Yu and more! Read the latest research in experimental hematology now on www.exphem.org.
Have you ever wondered about Pig HSCs? Today is your lucky day! Check out this excellent work from @ganuzalab.bsky.social. Well done!
Pig and human adult hematopoietic stem and progenitor cells are overall transcriptionally similar. www.exphem.org/article/S030...
@isehsociety.bsky.social
Merry Xmas to you and your family from our lab. 🎅🎄🎉🎄🎅☃️☃️🎉
