🌎 🧬 🖥️ logan-search.org the tool to query all SRA sequences (Dec 2023 snapshot) — just got major updates. Here's what's new. 🧵 1/12
I had fun writing a short commentary on the importance of integrating prophage biology into microbiome research 🦠
Now out in @cp-cellhostmicrobe.bsky.social
#microbiomesky #phagesky
www.cell.com/cell-host-mi...
Pleased to see this beautiful paper out. Kudos to @jeroenmeijer.bsky.social who took @stevenquistad.bsky.social data and dug deep, revealing a new phage that erupts to astonishing abundance. As theory predicts, the life of SGEs is fuelled by encounters with new hosts
www.science.org/doi/10.1126/...
Viruses are highly abundant in the oceans, but there is one place you won't typically find them: in global ocean ecosystem models... until now.
Introducing "vDarwin", an explicit integration of viruses into the MITgcm/Darwin global ecosystem framework:
www.biorxiv.org/content/10.6...
a 🧵
Pierre Peterlongo
Prophages are pervasive in the human gut yet largely overlooked in microbiome research,
despite substantial functional potential. Emerging evidence indicates that prophages
regulate bacterial fitness,...
www.cell.com
A single bacteriophage can dominate microbial communities yet only evolves when migration changes its ecological context.
Are gut phages friends or foes?
A nice "forum" in Cell Host&Microbe by @naamagz.bsky.social discussing it's all about context. Depending on host inflammation and ecology, phages can shift between stabilizing and destabilizing our microbiome.
www.cell.com/cell-host-mi...
#phagesky
New preprint! 🚨
Phage proteins don't act alone. Phages rely on homooligomerisation to assemble identical protein subunits into functional forms. But figuring out those exact configurations experimentally is tough. Learn about our approach in our new preprint! 👇 (1/n)
www.biorxiv.org/content/10.6...
Like a prophage being awakened from its slumber, the phage field has seen a lot of renewed activity during the last decade. Check out our new @natrevmicro.nature.com review on the temperate phage life cycle here to stay up-to-date 🧫🦠
www.nature.com/articles/s41...
Paul Rainey
Joshua Weitz
Gut bacteriophages defy simple classification as beneficial or harmful, instead shifting
between roles that stabilize or destabilize microbial communities depending on phage
lifestyle dynamics, host i...
I am hiring a Data Curator in my group nikolay-oskolkov.com/metabolic-re...! This is an excellent opportunity for anyone interested in multi-omics data analysis, exploratory (unsupervised) machine learning, and data management/curation. Apply here: euraxess.ec.europa.eu/jobs/443793. Appreciate RT!
The life cycle of temperate bacteriophages involves lytic or lysogenic cycles and has historically served as a model for studying genetic regulation. This Review provides an updated overview of these ...
