It's official, our med chem Senior Research Associate @hannahstewart92.bsky.social is the world's fastest scientist @guinnessworldrecords.com guinnessworldrecords.com/world-record...
Prof. Mike Waring (@mikewaring.bsky.social), Chair of Medicinal Chemistry, Newcastle University #facesofscience #chemsky #sciencesky
This work also provides some hopefully useful information on how to generate and interpret SAR of covalent inhibitors.
Group trip to the pub / watch the bins being emptied.
Starting the @mosmedcdt.bsky.social conference. It will get better from here!
New paper out in J Med Chem showing that covalent targeting of C775 has the potential to treat osimertinib resistant lung cancer. Really proud of this work and the team that did it! @nudrugdiscovery.bsky.social @nucancer.bsky.social @crhorizons.bsky.social pubs.acs.org/doi/10.1021/...
New paper: We've always used TPGS in our micellar #DEL synthesis. This paper shows you can find better ones using @baonguyengroup.bsky.social surfactant map. Great work from Jake Odger et al pubs.rsc.org/en/Content/A...
New paper published today describing some SAR on EGFR inhibitors including an interesting effect of a pair of enantiomers on covalent biinding www.nature.com/articles/s42...
