Think we’ve captured a hedgehog courtship ritual on camera last night. Fingers crossed for some hoglets in a couple of months
Happy to see our work describing an avidity mechanism of extracellular BMP regulation out. A great team effort from all involved!
Just seen a local post box with a crocheted topper with 22 bees remembering each victim of the Manchester Arena bombing ❤️
It's Postdoc Appreciation Week - thanks to all the fabulous postdocs in the Ashe lab for their hard work and collegiality!
Biblical!
Not sure what the collective noun is for tadpoles
Fun @mcf-uom.bsky.social celebration event today. Nice to see team LEAF being recognised for all the hard work in helping the MCF labs get LEAF gold awards. And good to celebrate Ali’s paper again!
Upon germline stem cell loss, cytonemes are necessary for differentiating germ cells to reaccess the self-renewal BMP signal, recolonize an empty niche, and dedifferentiate to germline stem cells. Our data also reveal how other cells can act as a physical barrier to cytoneme-target cell contact.
Our work on germline stem cell cytonemes and BMP signalling is finally published! A great team effort from the Ashe lab, @wilcocksonscott.bsky.social and @shukryjhabib.bsky.social.
www.pnas.org/doi/epdf/10....
We show that Drosophila ovarian germline stem cell cytonemes are required for asymmetric signalling, niche occupancy, and fitness during homeostasis. We also establish a new S2 cell-based model for studying BMP cytonemes.
