New research by Amelia R Tanner (cupediatrics.bsky.social) et al. investigated the effects of 9 days of glucagon infusion (5 or 50 ng/kg/min) in late-gestation fetal sheep, increasing plasma glucagon concentrations by ~800% to study chronic fetal hyperglucagonemia.
đź”— doi.org/10.1530/JOE-25-0447
A new study by Kuan-Chan Chen et al. provides insight into the physiological function and role of bone marrow adipose tissue (BMAT) in caloric restriction (CR)–associated skeletal and metabolic health.
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🧬 How does CXCL13 contribute to obesity-related multi-organ complications?
A new review by Mengke Huang et al. elucidates the pivotal role of C‑X‑C motif chemokine ligand 13 (CXCL13) in obesity-associated metabolic inflammation.
Read the article #openaccess: doi.org/10.1530/JOE-25-0295
A new hot-topic review by Melissa Emily Wright, Aled Rees, and Kevin Murphy discusses how advanced neuroimaging applications could provide new insights into the pathophysiology of polycystic ovary syndrome (PCOS; recently renamed to PMOS).
đź”—Read the review: doi.org/10.1530/JOE-...
New research by Yiwen Jiang et al. investigates the role of brain-derived membrane-initiated estrogen receptor-α (mERα) signalling in bone metabolism using a POMC-C451Af/f mouse model, in which mERα signalling is selectively inactivated in POMC-expressing neurons.
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🏆 We're thrilled to award the Q1 Editors' Choice Award to:
Fat’s all, folks: culturing and manipulating peri-prostatic adipocytes to probe impacts on prostate cancer biology
By Nil Grunberg et al.
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Thanks to the authors for your outstanding contribution đź‘Ź
We celebrate impactful figures published in Journal of Endocrinology through our Editors' Choice Figure Award.
The Q1 winner is Figure 3 in 'Clocks on steroids: how glucocorticoid receptors tell cells the time' By Anna Edmondson et al.
đź”— doi.org/10.1530/JOE-25-0340
Congratulations to the authors!
New research by Qiong Wu et al. identifies numerous dysregulated lncRNAs through microarray analysis of human preadipocytes and differentiated adipocytes, with a focus on lncRNA521141 as a regulator of adipogenic differentiation.
Read the research: doi.org/10.1530/JOE-...
Journal of Endocrinology
⏰ Glucocorticoids synchronise cellular circadian rhythms via canonical and rapid non‑canonical GR signalling, but the exact mechanism remains unclear. This review outlines current knowledge, key gaps, and how disrupted GC rhythms contribute to circadian‑linked disease.
doi.org/10.1530/JOE-25-0340
