S.O.A.P. Team in Nantes, France
Led by Julie Gavard & Nicolas Bidere
Signaling in Oncogenesis, Angiogenesis, and Permeability
#glioblastoma #cancer #research
LabSoap
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This week #JournalClub @labsoap.bsky.social @embojournal.org @komanderlab.bsky.social #ubiquitin #DUB #USP9X link.springer.com/article/10.1...
This week #JournalClub @labsoap.bsky.social #YAP #PROTAC #cancers @natureportfolio.nature.com www.nature.com/articles/s41...
Just Published !
onlinelibrary.wiley.com/doi/10.1111/...
Just Published !
onlinelibrary.wiley.com/doi/10.1111/...
This week #JournalClub @labsoap.bsky.social #stemcell #lunginjury #cancer #IGF @science.org www.science.org/doi/10.1126/...
Traffic Light Commentary—Src in the Upside Down: A Kinase Turned Inside Out - Gavard - 2026 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
This week #JournalClub @labsoap.bsky.social @cellpress.bsky.social @karimaj.bsky.social #virusinavirus #virus #spreading www.cell.com/cell/fulltex...
This week #JournalClub @labsoap.bsky.social #lysosome #brain @cellpress.bsky.social @abu-remaileh.bsky.social www.cell.com/cell/fulltex...
Just Published !
onlinelibrary.wiley.com/doi/10.1111/...
This week #JournalClub @LabSoap @nature.com #mitochondria transfer #astrocyte #neuron #nanotube Mitochondrial transfer from glia to neurons protects against peripheral neuropathy www.nature.com/articles/s41...
The ubiquitin-specific protease (USP) USP9X is a human deubiquitinase (DUB) with a large number of described targets and cellular roles. In cancer, USP9X is found as an oncogene or as a tumour suppres...
link.springer.com
YAP is a key oncogenic driver that has long been considered undruggable. Here, the authors present the development of a nanobody-based bioPROTAC that efficiently degrades endogenous YAP, demonstrating...
Fluorescent proteins fused with nuclear (NLS) or nucleolar (NoLS) localization signals are commonly used for live assessment of protein accumulation in the nucleus and nucleolus. We present a standar...
onlinelibrary.wiley.com
Loss of the cargo receptor Erv14 in Saccharomyces cerevisiae results in sensitivity to calcium, zinc, neutral extracellular pH, and elevated temperature. Furthermore, cells deleted in the ERV14 exhib...
Stem cells proliferate after injury to repair damaged tissue, and chronic injury can promote cancer. However, the injury-activated signals and regulatory mechanisms, and their relationship to cancer, ...
www.science.org
Just as Antelope Canyon transforms familiar rock into an unexpected hidden landscape, the topological inversion of Src reveals an unforeseen extracellular facet of kinase signaling in cancer. Antelop...
This study describes the cell-type-specific lysosomal proteome across the major brain
cell types and identifies SLC45A1 as a neuron-specific lysosomal sugar exporter linked
to lysosomal storage diseas...
www.cell.com
www.cell.com
McKellar et al. have discovered that some satellite viruses act as the ultimate hitchhikers.
They physically become a virus inside a virus, hiding within helper virus particles
by hitching a ride as a...
Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is...
onlinelibrary.wiley.com
Mitochondria that are transported from satellite glial cells in dorsal root ganglia to peripheral sensory neurons through tunneling nanotube-like structures provide protection against peripheral neuro...
