This week #JournalClub @labsoap.bsky.social #YAP #PROTAC #cancers @natureportfolio.nature.com www.nature.com/articles/s41...
YAP is a key oncogenic driver that has long been considered undruggable. Here, the authors present the development of a nanobody-based bioPROTAC that efficiently degrades endogenous YAP, demonstrating...