There is a lot of undescribed prokaryotic diversity in existing whole-genome metagenomic data!
www.nature.com/articles/s41...
Our latest work is now online!
Explored how obesogenic diets, obesity, and key experimental factors (mouse vendor, sex, microbiota) influence intestinal antimicrobial peptide (AMP) expression
www.nature.com
Re-analysis of over 92,000 metagenomes reveals hundreds of thousands of previously undescribed Bacterial and Archaeal clades hidden in plain sight.
Our study on disentangling the impact of #obesity, #diet, host factors, and #microbiota on small intestinal #antimicrobialpeptide expression is now published in Gut Microbes!
Fantastic work by Fabiola Puértolas-Balint et al!
#microbiomesky #microsky #GastroSky
www.tandfonline.com/doi/full/10....
The small intestinal mucosa has the delicate task of allowing absorption of nutrients and limiting microbial colonization at the mucosal surface through production of antimicrobial peptides and pro...
Happy and grateful to have contributed to this work. Excited to share a new publication from the Sebastian Group at APC Microbiome Ireland. Many thanks to @tsbschm.bsky.social for the guidance and continued support. Congratulations to all co-authors
🚀 Excited to be part of this study! 🧪
Our research shows that a milk-derived peptide✨ can boost intestinal mucus function even with low fiber intake 🌾⬇️ — opening the door to a potential new prebiotic 🌱 for supporting gut health 💪🩺.
Vishnu Prasoodanan, PhD
Vishnu Prasoodanan, PhD
Our study describing `microntology` and annotations for >300k metagenomes is now online in Bioinformatics @academic.oup.com :
academic.oup.com/bioinformati...
Congratulations to @fullam.bsky.social @vishnuprasoodanan.bsky.social & @biocs.bsky.social !
See the thread below for more details.
AbstractMotivation. Data-enabled studies of microbial ecology and evolution depend on high-quality descriptions of microbial habitats, based on curated and
academic.oup.com
Summer strike #2: Our collaboration work with Arla Foods Ingredients has just been published in Food Research International:
www.sciencedirect.com/science/arti...
#microsky #gastrosky #microbiomesky #guthealth
The colonic mucus layer is the primary interface between the host and the gut microbiota. It serves both as an ecological niche for bacteria and a bar…
Most microbial diversity is still missing from genome catalogues.
A new paper in @natmicrobiol.nature.com analysed 92,187 metagenomes and found that most discoverable bacterial and archaeal lineages sit in unbinned contigs.
📰 buff.ly/Q5XREM7
#Microbiome #Metagenomics
@vishnuprasoodanan.bsky.social
A clearer way to describe microbial habitats helps researchers compare #microbiome data.
A new paper in #𝐁𝐢𝐨𝐢𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐜𝐬 introduces microntology: 148 terms and curated annotations for 305,626 #metagenomic samples.
@tsbschm.bsky.social @embl.org @vishnuprasoodanan.bsky.social
📰 buff.ly/FD1SYYJ
APC Microbiome Ireland
APC Microbiome Ireland
We just released a @biorxivpreprint.bsky.social describing the *microntology*, a lightweight controlled vocabulary that we have been using for a while to tag metagenomes with contextual data.
Study by @fullam.bsky.social @vishnuprasoodanan.bsky.social et al:
1/
www.biorxiv.org/content/10.6...
We just released a @biorxivpreprint.bsky.social describing the *microntology*, a lightweight controlled vocabulary that we have been using for a while to tag metagenomes with contextual data.
Study by @fullam.bsky.social @vishnuprasoodanan.bsky.social et al:
1/
www.biorxiv.org/content/10.6...
Summary. We introduce microntology v1.0, a pragmatic controlled vocabulary of 148 terms to describe microbial habitats and lifestyles, and provide manually curated microntology annotations for >300k m...
Summary. We introduce microntology v1.0, a pragmatic controlled vocabulary of 148 terms to describe microbial habitats and lifestyles, and provide manually curated microntology annotations for >300k m...
www.biorxiv.org
We hope many of you will find it useful, and will continue to add data. Here's the preprint: www.biorxiv.org/content/10.1... - hopefully coming soon to a NAR Database Issue near you 😅 Thanks to everyone in the @borklab.bsky.social @embl.org who contributed to this! 7/7
www.biorxiv.org
Metagenomic sequencing enables the in-depth study of microbes and their functions in humans, animals and the environment. While sequencing data is deposited in public databases, the associated context...
I will write more after the Easter break, but for now congratulations to @vishnuprasoodanan.bsky.social @omaistrenko.bsky.social and all other co-authors (including @fullam.bsky.social @pangenomics.bsky.social @luispedrocoelho.bsky.social @anja1.bsky.social )!
