AI and tissue clearing-based technologies for health.
Director at Helmholtz Munich, Full professor at LMU Munich, and CEO of Deep Piction (@deeppiction.bsky.social)
We’re🇩🇪🇹🇷🇭🇷🇨🇳🇮🇹🇮🇳🇸🇮🇴🇲🇨🇱🇭🇺🇧🇬🇺🇦🇷🇴🇦🇹🇹🇼🏳🌈
Ali Maximilian Erturk
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Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage.
Proud to see >75K accesses & >60 news stories in the first week. Paper->> www.nature.com/articles/s41... Next www.biorxiv.org/content/10.6...
Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell.
In obesity, it revealed body-wide inflammation & unexpected facial nerve damage.
www.nature.com/articles/s41...
More at: x.com/erturklab/st...
Ohhh, wow!
Nature research paper: A deep-learning framework reveals whole-body perturbations at cell level
go.nature.com/3Pjox61
Video
I was not very much involved in this project from our lab, but I can honestly say that I find this story really amazing!
Ali Maximilian Erturk
Super happy to see our work published in @nature.com last week 🤩 By combining whole-body tissue clearing, light-sheet microscopy and AI, we mapped obesity-associated remodeling across the entire mouse body in 3D at cellular resolution.
www.nature.com/articles/s41...
@erturklab.bsky.social
MouseMapper
An imaging-omics workflow of whole-mouse analysis
Up to single-cell resolution!👹
vDISCO WildDISCO whole-mouse optical clearing
#SpatialProteomics Trigeminal ganglia
VR annotation of major organs, peripheral nerve & Mφ
@erturklab.bsky.social Nature 2026
www.nature.com/articles/s41...
A deep-learning framework reveals whole-body perturbations at cell level @nature.com @erturklab.bsky.social @dorie00.bsky.social
www.nature.com/articles/s41...
Ali Maximilian Erturk
#M1 Launches First Funding Period & Advances Translation in Munich🚀
Seven projects receive €7.45 million through the M1 – Munich Medicine Alliance.
#HelmholtzMunich is involved in four funded projects.
👉 t1p.de/disle
@tum.de @lmu.de @boyanbonev.bsky.social @erturklab.bsky.social
#MunichMedicine
AI Atlas Reveals Hidden Whole-Body-Damage Caused by Obesity
Researchers around Prof. Ali Ertürk, #HelmholtzMunich, developed #MouseMapper – an #AI framework that maps disease-related changes throughout the entire mouse body at cellular resolution.
👉 t1p.de/svfv0
@erturklab.bsky.social
An analysis of diet-induced obesity using MouseMapper—a suite of foundation-model-based deep-learning algorithms—identifies structural alterations of the infraorbital branch of the trigeminal ganglia.
Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage.
Proud to see >75K accesses & >60 news stories in the first week. Paper->> www.nature.com/articles/s41... Next www.biorxiv.org/content/10.6...
Video
Ali Maximilian Erturk
🧠 Does brain aging always mean vessel loss?
We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage.
Check it out below!
www.biorxiv.org/content/10.6...
