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#ScienceRevolution #PeerImprovement #DiscoveryStackPilot #immunosky
In @jem.org, Kuhn, @maxkrummel.bsky.social et al. demonstrate how local gene editing of cancer-associated fibroblasts alters their cell state and, subsequently, the cellular tumor microenvironment rupress.org/jem/article/...
#TME #CAFs #TumorImmunology
Kuhn, @maxkrummel.bsky.social et al. demonstrate how local gene editing of cancer-associated fibroblasts alters their cell state and, subsequently, the cellular tumor microenvironment rupress.org/jem/article/...
#TME #CAFs #TumorImmunology
Intravital imaging of pulmonary lymphatics in #inflammation and metastatic cancer. A new imaging approach developed by Simon Cleary (@simoncleary.bsky.social), Longhui Qiu, Mark Looney and colleagues: https://buff.ly/41msQjZ
@maxkrummel.bsky.social
Registration is now open and an all-in roster of immunologists anchor the premiere Dendritic cell meeting. www.dc2026sandiego.com/invited-spea... Sunny (blue state) San Diego. Sessions devoted to honoring 15 year anniversary of Nobel prize (Steinman) and translational advances…what is not to like.?
I just got this from the site for the meeting. Looks lovely @idoyagalab.bsky.social I might imagine @shalinhnaik.bsky.social getting out in his yacht after the sessions!
Many tx studies (Mujal... Azizi…)failed to validate M1/M2 signatures in vivo. Many also suspected that calling cells bearing ‘prototypical M2’ genes ‘‘immunosuppressive’ was simplistic + incorrect. Nonetheless many (us too!) leaned on the simplification. Arja addresses the reality head on…thnx JEM
If dendritic cells are part of your science,
#DC2026 should be part of your year!
🌍Global DC community in San Diego
✳️New biology & discoveries
Abstracts & registration are OPEN
www.dc2026sandiego.com
⭐️ Come for the science. Stay for the community. @maxkrummel.bsky.social @zunigalab.bsky.social 🔁
How will our increasingly deep understanding of diverse immune archetypes in cancers guide our search for cures?
This perspective describes a future in which we discover drugs based on transitions of tissue/immunobiology through intermediate states, to health. authors.elsevier.com/a/1llig5TA51...
