In this cohort study, Gabriella Silva and colleagues evaluate different definitions of multimorbidity (count-based versus clustering) and their associations with prevalence, health profiles and mortality in UK Biobank participants 🧪 #MedSky
plos.io/4e8ySLE
Placenta accreta spectrum is a pregnancy complication caused by abnormal placental attachment to the uterus. In this Perspective, Eric Jauniaux &co discuss emerging pathophysiological evidence & argue that a reassessment of definition, diagnosis & management is overdue🧪🤰 #MedSky
plos.io/4fM4nfQ
Is there a link between food additives & type 2 #diabetes incidence? Using data from the NutriNet-Santé cohort study, Payen de la Garanderie &co reveal positive associations between exposure to two widely consumed food additive mixtures & higher T2D incidence🧪 #DiabetesAwarenessWeek
plos.io/3S5F3Yf
🔔 In this systematic review and meta-analysis, Nicolò Lentini and colleagues investigate the clinical impact of therapies recommended by Molecular Tumor Boards on patient outcomes. 🧪 #MedSky
Are non-steroidal anti-inflammatory drugs (NSAIDs) like #ibuprofen safe to take during the first trimester of pregnancy? In this Perspective, Kenneth Man & Andrew Yuen highlight new evidence on the safety of first-trimester NSAID use and congenital malformation risk 🧪 #MedSky #pain
plos.io/4xaLdGs
It's #DiabetesAwarenessWeek, and this Perspective highlights exciting developments in preventative & stem cell-based therapies for T1D, discussing the prospects & hurdles of arresting or reversing the disease & achieving insulin independence for type 1 diabetics🧪 #MedSky #diabetes
It's #DiabetesAwarenessWeek! 📣
How can we better predict diabetic retinal neurodegeneration (DRN)? In this observational multi-cohort study, Wei Wang and colleagues identify circulating plasma protein signatures of DRN and translate them into a risk prediction system 🧪 #MedSky
This Policy Forum by Saul Martin-Rodriguez &co outlines why strengthening enforceable #data & #code sharing mechanisms is required to ensure validity & transparency of research, focusing on systematic reviews & meta-analyses that underpin clinical guidelines & #health policy🧪 #MedSky
plos.io/4uCWixt
In Latin America, rising incarceration has fueled the #tuberculosis epidemic. In this modeling study, Liu & co demonstrate that prison screening for TB at entry, exit & biannually is predicted to have a substantial impact on TB incidence in both prisons & general populations🧪 #MedSky
plos.io/4g25asX
📣 In this machine learning study, Patrick Staunton and colleagues develop and test a model to predict hospitalisation in children under 5 years of age with pneumonia in Malawi. 🧪 #MedSky
In this cohort study, Gabriella Silva and colleagues evaluate different definitions of multimorbidity (count-based versus clustering) and their associations with prevalence, health profiles and mortal...
plos.io
In this Perspective, Jonathan Evans and colleagues discuss why restricting access to joint replacement surgery based on BMI alone is not supported by evidence, and highlight how such rest rictions ris...
Using data from the NutriNet-Santé cohort study, Marie Payen de la Garanderie and colleagues investigate potential interactions of food additives in five commonly consumed food additive mixtures and t...
In this systematic review meta-analysis, Nicolò Lentini and colleagues investigate the clinical impact of therapies recommended by Molecular Tumor Boards on patient outcomes.
In this Perspective, Kenneth Man and Andrew Yuen highlight a recent PLOS Medicine study that presents new evidence on the safety of first-trimester NSAID use and congenital malformation risk, but disc...
plos.io
This Perspective highlights exciting developments in preventative treatments and stem cell-based therapies for type 1 diabetes, discussing the prospects and hurdles of arresting or reversing the…
In a observational multi-cohort study, Wei Wang and colleagues identify circulating plasma protein signatures of diabetic retinal neurodegeneration (DRN) and translate them into a risk prediction…
plos.io
Systematic reviews and meta-analyses underpin clinical guidelines and health policy, yet their validity may be compromised by limited access to underlying datasets and associated analytical code. This...
plos.io
In a mathematical modeling study, Yiran Liu and colleagues demonstrate that screening for tuberculosis (TB) in prisons in Peru, Colombia and Brazil at entry and exist and biannually is predicted to ha...
In a machine learning study, Patrick Staunton and colleagues develop and test a model to predict hospitalisation in children with pneumonia under 5 years of age in Malawi.
