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Leading open access health science journal publishing impactful research that transforms global healthcare and advances clinical understanding. 🔗 https://journals.plos.org/plosmedicine
PLOS Medicine









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📣 In this machine learning study, Patrick Staunton and colleagues develop and test a model to predict hospitalisation in children under 5 years of age with pneumonia in Malawi. 🧪 #MedSky
In this cohort study, Gabriella Silva and colleagues evaluate different definitions of multimorbidity (count-based versus clustering) and their associations with prevalence, health profiles and mortality in UK Biobank participants 🧪 #MedSky plos.io/4e8ySLE
In Latin America, rising incarceration has fueled the #tuberculosis epidemic. In this modeling study, Liu & co demonstrate that prison screening for TB at entry, exit & biannually is predicted to have a substantial impact on TB incidence in both prisons & general populations🧪 #MedSky plos.io/4g25asX
🔔 In this systematic review and meta-analysis, Nicolò Lentini and colleagues investigate the clinical impact of therapies recommended by Molecular Tumor Boards on patient outcomes. 🧪 #MedSky
It's #DiabetesAwarenessWeek! 📣 How can we better predict diabetic retinal neurodegeneration (DRN)? In this observational multi-cohort study, Wei Wang and colleagues identify circulating plasma protein signatures of DRN and translate them into a risk prediction system 🧪 #MedSky
It's #DiabetesAwarenessWeek, and this Perspective highlights exciting developments in preventative & stem cell-based therapies for T1D, discussing the prospects & hurdles of arresting or reversing the disease & achieving insulin independence for type 1 diabetics🧪 #MedSky #diabetes
Are non-steroidal anti-inflammatory drugs (NSAIDs) like #ibuprofen safe to take during the first trimester of pregnancy? In this Perspective, Kenneth Man & Andrew Yuen highlight new evidence on the safety of first-trimester NSAID use and congenital malformation risk 🧪 #MedSky #pain plos.io/4xaLdGs
Is there a link between food additives & type 2 #diabetes incidence? Using data from the NutriNet-Santé cohort study, Payen de la Garanderie &co reveal positive associations between exposure to two widely consumed food additive mixtures & higher T2D incidence🧪 #DiabetesAwarenessWeek plos.io/3S5F3Yf
Placenta accreta spectrum is a pregnancy complication caused by abnormal placental attachment to the uterus. In this Perspective, Eric Jauniaux &co discuss emerging pathophysiological evidence & argue that a reassessment of definition, diagnosis & management is overdue🧪🤰 #MedSky plos.io/4fM4nfQ
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We are pleased to announce that @plosmedicine.org has introduced an updated code sharing policy to support greater transparency and trust in research. Find out more in the editorial ⬇️
Prediction of hospitalisation in young children with pneumonia in Malawi: A machine learning-based approach
In a machine learning study, Patrick Staunton and colleagues develop and test a model to predict hospitalisation in children with pneumonia under 5 years of age in Malawi.
plos.io
In a mathematical modeling study, Yiran Liu and colleagues demonstrate that screening for tuberculosis (TB) in prisons in Peru, Colombia and Brazil at entry and exist and biannually is predicted to ha...
plos.io
Comparative impacts and cost-effectiveness of tuberculosis systematic screening strategies in prisons in Brazil, Colombia, and Peru: A mathematical modeling study
In this systematic review meta-analysis, Nicolò Lentini and colleagues investigate the clinical impact of therapies recommended by Molecular Tumor Boards on patient outcomes.
plos.io
Molecular Tumor Boards clinical impact on patient care and structural features: A systematic review and meta-analysis
In a observational multi-cohort study, Wei Wang and colleagues identify circulating plasma protein signatures of diabetic retinal neurodegeneration (DRN) and translate them into a risk prediction…
plos.io
Proteomic signatures of early retinal neurodegeneration in type 2 diabetes mellitus
This Perspective highlights exciting developments in preventative treatments and stem cell-based therapies for type 1 diabetes, discussing the prospects and hurdles of arresting or reversing the…
plos.io
11d
Towards insulin independence in type 1 diabetes: Prospects for prevention and cure
In this Perspective, Kenneth Man and Andrew Yuen highlight a recent PLOS Medicine study that presents new evidence on the safety of first-trimester NSAID use and congenital malformation risk, but disc...
plos.io
Beyond associations: Navigating the safety of non-steroidal anti-inflammatory drugs (NSAIDs) in early pregnancy
Food additive mixtures and type 2 diabetes incidence: Results from the NutriNet-Santé prospective cohort
Using data from the NutriNet-Santé cohort study, Marie Payen de la Garanderie and colleagues investigate potential interactions of food additives in five commonly consumed food additive mixtures and t...
plos.io
PLOS Medicine
PLOS Medicine
PLOS Medicine
PLOS Medicine
PLOS Medicine
PLOS Medicine
PLOS Medicine
PLOS Medicine
PLOS Medicine
Recognizing that code is as essential a research artifact as the data it analyzes, this Editorial outlines how PLOS Medicine is strengthening its code sharing policy to further ensure reproducibility and trust in the scientific record 🧪 #MedSky #OpenScience plos.io/4wZmViS
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Recognizing that code is as essential a research artifact as the data it analyzes, this Editorial outlines how PLOS Medicine is strengthening its code sharing policy to further ensure reproducibility ...
plos.io
Requiring code sharing to strengthen transparency and trust in research
PLOS Medicine
Comparison of count-based and clustering definitions of multimorbidity and their association with prevalence of multimorbidity, health profiles, and mortality: A cohort study of UK Biobank participant...
In this cohort study, Gabriella Silva and colleagues evaluate different definitions of multimorbidity (count-based versus clustering) and their associations with prevalence, health profiles and mortal...
plos.io
In this Perspective, Jonathan Evans and colleagues discuss why restricting access to joint replacement surgery based on BMI alone is not supported by evidence, and highlight how such rest rictions ris...
plos.io
Placenta accreta spectrum in the 21st century: Challenging dogma and redefining disorder
PLOS