Laser scanning on your equipment entails tradeoffs between speed, resolution, and field-of-view. Pick 2 of those 3.
Now you can get all 3, with this breakthrough.
www.laserfocusworld.com/optics/artic... Thanks @laserfocusworld.bsky.social
We're at the MBL in Woods Hole, MA. Stop on by if you want to try it out for yourself.
2-photon imaging over a 3 mm x 3 mm field-of-view. The most compact mesoscale 2p also has the fastest scanning!
pacificoptica.com/ventana/
pacificoptica.com/cousa/
Huge field-of-view, fast, high res. two-photon imaging. This technology (paper link below) is available now, in the Ventana products.
Sold as complete turnkey systems, or components. pacificoptica.com/ventana/
Installations are happening now at some of the best labs in the world.
“Because scientific knowledge is tentative and provisional, it is the enemy of dogma.” -Baron Taverne
All Pacific Optica products are designed in Santa Barbara, California, USA.
“Because [science] is the most effective way of learning about the physical world, it erodes superstition, ignorance and prejudice, which have been at the root of the denial of human rights throughout history…” -Baron Taverne
FN > 45
Whatever objective you use, Ventana imaging systems will get more field-of-view out of it, with full NA, and diffraction limited. The best ever for multiphoton / two-photon.
And fast! 16,000 - 24,000 lines/s across the full field of view.
pacificoptica.com/ventana/
Loving the "CEO eats his own burger/hot dog/..." stuff.
Pacific Optica's CEO uses his own Ventana, Diesel2p, and Cousa products. They're the high throughput, turnkey, workhorse systems that power the lab.
pacificoptica.com/ventana/
pacificoptica.com/diesel2p/
pacificoptica.com/cousa/
An excited customer, sharing photos of the optics they just received.
And one of the first Avocado objectives in customer hands. It's a Cousa-class objective, with an NA of 0.6 and a WD of 10 mm, optimized for 2p, and excellent performance out to the edges of the field-of-view. More info soon!
Cool paper from Garret Stuber's lab and colleagues, led by Madelyn Hjort.
mPFC-VTA circuit for contingency degredation. doi.org/10.1038/s415...
Fig. 3 & 4 used the Cousa objective: **2p imaging + 2p holographic optogenetic stim., deep in brain using microprisms** !
pacificoptica.com/cousa/
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Two-photon calcium imaging at 24,000 lines/s, with the resonant axis spanning 4x what other systems can do. Inertia-free. Diffraction-limited. No tradeoffs. Che-Hang Yu developed a 4x angle multiplier for laser scanning. His paper is out today: opg.optica.org/optica/fullt... 1/n #fluorescenceFriday
