Third year PhD student at Julius Lukes Lab @BiologyCentre
Studying tRNAs and translation in protists.
Fadel Fakih
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A threonine-to-aspartate ACA codon reassignment in uncultivated Acidimicrobiales bacteria https://www.biorxiv.org/content/10.64898/2026.05.03.722492v1
This reassignment first emerged from our broader bacterial genetic code analysis in our recent Fakih et al. NAR 2026 (doi.org/10.1093/nar/...) and here we provide a detailed characterization of its phylogenetic, codon-usage, tRNA, and aminoacylation context.
We have a new preprint on a rare sense-to-sense genetic code reassignment in uncultivated Acidimicrobiales bacteria.
We report evidence that ACA, normally a threonine codon, is reassigned to aspartate in a RAAP-2 lineage.
#tRNA #PhD #evolution
Link: www.biorxiv.org/content/10.6...
Do experiments in model organisms reveal universal biological rules, or only local regularities shaped by evolutionary history?
Here is a short synthesis, inspired by our work, on how comparative genomics helps us distinguish between the two.
#PhD #Biology #RNA
rnastuff.com/2026/05/10/c...
