Publication alert! 🔔 Our recent work exploring how Plasmodium uses a Rad51 independent homologous recombination to diversify its var gene repertoire is now published in 🧬 Nucleic Acids Research! @oupprimary.bsky.social @narjournal.bsky.social Read more here.
tinyurl.com/794brb6h
Mechanistic insights into coordinated var transcriptional switching in malaria parasites
@kirkdeitsch.bsky.social and coworkers
link.springer.com/article/10.1...
link.springer.com
The exceptional virulence of the human malaria parasite, Plasmodium falciparum, is attributed to the adhesive properties of infected red blood cells and the parasite’s ability to avoid antibody recogn...
If you are searching for a postdoc position or know someone who does, cannot recommend this position enough!
🚨 New paper out! 🚨
🧬 Parasite sex as a discovery tool — new insights into Cryptosporidium virulence!
Huge thanks to my co-authors, collaborators & mentors 🙌
#Parasites #Cryptosporidium #Genetics #InfectiousDiseases #ForwardGenetics
www.sciencedirect.com/science/arti...
Excited to share our new paper, co-led by Gracyn Buenconsejo and me.
Why did a promising anti-#Cryptosporidium drug fail?
We asked whether the parasite itself might already be genetically prepared to escape treatment.
doi.org/10.1038/s415...
#Clofazimine #forwardgenetics
New paper out !
Want to learn more about fascinating proteasome biology and Artemisinin resistance in Malaria parasites ? Check out our preprint:
www.biorxiv.org/content/10.1...
Our latest story on Clofazimine resistance in Cryptosporidium! What started as a side project turned into one of the most interesting stories.
Genetics 101 😊
#Cryptosporidium #Apicomplexa #Clofazimine #AntimicrobialResistance #AMR #ParasiteResearch
www.biorxiv.org/content/10.1...
Happy International Day of Women and Girls in Science! Let’s continue to support and celebrate them, and fight for equal opportunities for women in STEM! Shout-out to @shubhabevkal.bsky.social and @fra-florini.bsky.social! You’re the best!
#WomenInScience #WomenInSTEM
The relationship between parasite genotype and pathogenesis is largely unknown for Cryptosporidium, a leading cause of diarrheal disease in children. …
Registration & abstract submission are open for the 37th Molecular Parasitology Meeting (MPM XXXVII) 🧫
@MJGubbels @Deepali_Ravel @omartheharb
Sept 13–17, 2026 | Woods Hole, MA + virtual
Abstract deadline: June 19
@rmc9z.bsky.social @mjgubbels.bsky.social @omarharb.org
parasitesrule.com/mpm-xxxvii
Forward and reverse genetics identifies the mode of action of clofazimine in the parasite Cryptosporidium. The genomic locus encoding the target is heterogeneous, and a resistance-conferring allele is...
The ubiquitin-proteasome system (UPS) is essential for Plasmodium falciparum to maintain protein homeostasis, adapt to proteotoxic stress, and regulate parasite growth and stage transitions. The prote...
The parasite Cryptosporidium is a leading cause of life-threatening diarrheal disease, and effective treatment is not available. The discovery of potent anti-Cryptosporidium activity of clofazimine, o...
www.biorxiv.org
Sebastian Shaw
Sebastian Shaw
Sebastian Shaw
Sebastian Shaw
Shubha Bevkal
🚨 Postdoc position 🚨
I’m moving back to Switzerland this summer to launch my lab at the University of Zurich and am recruiting a Postdoctoral Fellow (start: late 2026).
Details & application:
jobs.uzh.ch/job-vacancie....
Please share! 😊
The newly founded Cryptosporidium lab at the Institute of Parasitology focuses on the genetic and transcriptomic basis of parasite virulence and persistence in Cryptosporidium and is committed to incl...
🚨New paper out 🚨 Excited to see this work from Joe Visone and me published! We dissect the molecular mechanisms behind var2csa transcription and translation. Take a look👇 link.springer.com/article/10.1...
The exceptional virulence of the human malaria parasite, Plasmodium falciparum, is attributed to the adhesive properties of infected red blood cells and the parasite’s ability to avoid antibody recogn...
