📢 New publication.
We answered an old question in structural biology: (how) does the crystal lattice impact proteins? In particular, how does the crystal restrict the protein's dynamics?
We used local probes of dynamics: the rotation of aromatic rings. 🧵
www.nature.com/articles/s41...
After his fight at the White House, Sean O'Malley threw up what the announcers described as a "salute" to "the troops" and Trump
If this is true,: WTF?
The extent to which crystal packing constrains protein dynamics is hard to decipher. Now a combination of NMR, crystallography and molecular dynamics simulations show that intermolecular contacts can ...
One of the Climbers With Hillary Dawa Speaks Out About What Happened on Everest explorersweb.com/one-of-the-c...
An innovative technology boosts image quality for protein structures idp.nature.com/authorize?re...
Russia has bombed the Kyiv Pechersk Lavra overnight, a UNESCO World Heritage Site founded in 1051 and sacred to Christians, older than Moscow. The Uspenskiy Cathedral is currently on fire. The Lavra is listed under Enhanced Protection under the Second Protocol to the 1954 Hague Convention.
Nature research paper: Whole-genome duplication shaped cell-type evolution in the vertebrate brain
go.nature.com/4uyh9C1
idp.nature.com
Cancer and cell aging studies may have relied on antibodies to incorrect molecule
After years of effort, two research teams have developed ‘laser phase plate’ systems that could help cryo-electron-microscopy users to generate high-quality structures for a broad range of proteins.
Analyses of brain single-cell transcriptomes from human, mouse, lizard, lamprey and amphioxus reveal that duplicated genes (ohnologues) played a pivotal part in early vertebrate cell-type diversification.