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📢 New publication. We answered an old question in structural biology: (how) does the crystal lattice impact proteins? In particular, how does the crystal restrict the protein's dynamics? We used local probes of dynamics: the rotation of aromatic rings. 🧵 www.nature.com/articles/s41...
After his fight at the White House, Sean O'Malley threw up what the announcers described as a "salute" to "the troops" and Trump
If this is true,: WTF?
13h
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The extent to which crystal packing constrains protein dynamics is hard to decipher. Now a combination of NMR, crystallography and molecular dynamics simulations show that intermolecular contacts can ...
www.nature.com
Aromatic ring flips reveal reshaping of protein dynamics in crystals and complexes - Nature Chemistry
www.science.org/content/arti...
idp.nature.com/authorize?re...
ML
Hunter Walker
16h
One of the Climbers With Hillary Dawa Speaks Out About What Happened on Everest explorersweb.com/one-of-the-c...
3d
An innovative technology boosts image quality for protein structures idp.nature.com/authorize?re...
2d
Russia has bombed the Kyiv Pechersk Lavra overnight, a UNESCO World Heritage Site founded in 1051 and sacred to Christians, older than Moscow. The Uspenskiy Cathedral is currently on fire. The Lavra is listed under Enhanced Protection under the Second Protocol to the 1954 Hague Convention.
2d
Nature research paper: Whole-genome duplication shaped cell-type evolution in the vertebrate brain go.nature.com/4uyh9C1
idp.nature.com
8h
Cancer and cell aging studies may have relied on antibodies to incorrect molecule
www.science.org
4d
Protein name confusion created antibody mix-up affecting hundreds of papers
Mariusz Chmielewski, one of two clients with Hillary Dawa on Everest the day the Sherpa disappeared, tells the story of that disorganized descent.
explorersweb.com
One of the Climbers With Hillary Dawa Speaks Out About What Happened on Everest » Explorersweb
Arne Elofsson
Arne Elofsson
After years of effort, two research teams have developed ‘laser phase plate’ systems that could help cryo-electron-microscopy users to generate high-quality structures for a broad range of proteins.
An innovative technology boosts image quality for protein structures
idp.nature.com
Arne Elofsson
Arne Elofsson
Analyses of brain single-cell transcriptomes from human, mouse, lizard, lamprey and amphioxus reveal that duplicated genes (ohnologues) played a pivotal part in early vertebrate cell-type diversification.
go.nature.com
Whole-genome duplication shaped cell-type evolution in the vertebrate brain - Nature
Nature
SlavaUkraini033
Preprint #4: ESMFold2 biohub.ai/models/esmfo...
17h
ESMFold2 predicts high-resolution, all-atom 3D protein structures from sequence.
biohub.ai
ESMFold2 Protein Structure Prediction
Stephanie Wankowicz