5/ 💻 Surprise package! We developed a custom pipeline, deNOVOEnrich, to profile somatic TE insertions from TEd-seq short-read data.
Using split-read mapping, we pinpoint new somatic insertions at base-pair resolution 🧬🔍
Check it out: github.com/hAmbreen02/d...
2/ Combining distinct experimental conditions, we traced a roadmap of expected TE movement in somatic cells 🌿, capturing ~200K new TE insertions across multiple families in the process.
6/ 🙏 Huge thanks to the amazing collaborators and co-authors who made this work possible!
🧑🔬 Basile Leduque, Leandro Quadrana, Keith Slotkin, Alexandros Bousios (@abousios.bsky.social) & Hans-wilhelm Nuetzmann