New paper out today in PRX Life!
We developed a stochastic transport model showing how antibiotic-induced ribosome pausing may trigger collective jamming on mRNA, with longer transcripts paying a disproportionate price.
Read it here! 👇
🔗 doi.org/10.1103/vrqp...
“Units of the NIH are privately directing grantees to request permission in advance for any co-authorship with a scholar affiliated with a foreign institution, even if all the work was done in the United States.”
Grantees also told to remove papers with foreign authors from progress reports.
jmc2026.sciencesconf.org
physics of bacteria and other microorganisms, which will take place at the next Condensed Matter Days in Toulouse, 26-30 october 2026.
Submission open for the ninth YBM Meeting (deadline - 19th February)! Abstract submission link: forms.gle/SBeQeAp9MR2U...
Saeed's paper is now published:
"PURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized proteins"
www.nature.com/articles/s41...
New SPCG paper. With the Bokinsky lab (Milan Lacassin), Andrea Ripamonti modeled the competition for transcriptional resources. Our data and model jointly show how E. coli’s second messengers ppGpp & cAMP reshape gene expression globally.
www.sciencedirect.com/science/arti...
Carl T. Bergstrom
Luca Ciandrini
Some molecular machines, like ribosomes, can persist for long periods of time in cells.
Could molecular aging of ribosomes shape how proteins are made?
In our new preprint we track ribosomes as they age in cells and uncover unexpected effects on translation (1/10)
www.biorxiv.org/content/10.6...
Young Biophysicists Meeting
Maerkl Lab
Statistical Physics of Cells and Genomes
Biophysical Paris
Jordy F. Botello
NIH, NASA grantees are confused and concerned amid agencies’ piecemeal communication
Cells regulate gene expression by balancing transcriptional resources across different functional groups of genes. In Escherichia coli, second messeng…
Building a self-replicating biochemical system remains a challenge in synthetic biology. Here the authors demonstrate that the cell-free protein synthesis PURE system can be reconstituted from protein...
