New SPCG paper. With the Bokinsky lab (Milan Lacassin), Andrea Ripamonti modeled the competition for transcriptional resources. Our data and model jointly show how E. coli’s second messengers ppGpp & cAMP reshape gene expression globally.
www.sciencedirect.com/science/arti...
Cells regulate gene expression by balancing transcriptional resources across different functional groups of genes. In Escherichia coli, second messeng…