Inlay

University of Michigan Life Sciences Institute—exploring biological processes, structures and functions at the finest scale to create impact on a global scale.

What to viruses have to do with cancer? Microbiologist @drsprggs.bsky.social explains why her lab is probing the pathways that viruses use to get into a host cell's nucleus, and how this research can shed light on the ways viruses either induce or combat cancer: www.youtube.com/watch?v=7f_Q...

Applications for the 2026 #CryoET Data Processing Workshop are due one month from today! Learn more about this hands-on workshop and apply by March 20: myumi.ch/lsi-cryo-workshop-2026

The LSI labs of David H. Sherman and Filipa Pereira have teamed up to boost bacterial production of a long-elusive compound, leading to a potential new treatment for drug-resistant malaria. Read more: research.umich.edu/research-sto...

Congratulations to LSI faculty member David Ginsburg, who has received the @isth-official.bsky.social 2026 Outstanding Mentor Award in honor of his "ongoing commitment to cultivate and mentor early career professionals in the thrombosis and hemostasis field."

LabGym, an open-source AI software from the @byneuron.bsky.social lab, offering new insights into organisms from fruit flies to Japanese macaques to jaguars. "... LabGym is here to democratize the use of AI for behavior analysis." www.lsi.umich.edu/news/lsi-mag...

In a new "Look to Leadership" column, LSI Director Roger Cone discusses the importance of using programs such as the Aspirnaut Summer Research Internship to provide life-changing opportunities for future scientists. myumi.ch/Nrqrk

The deadline to register for the 2026 Cryo-ET Workshop has been extended extended to April 10! Learn more about this hands-on workshop and apply at: myumi.ch/lsi-cryo-workshop-2026 @jbquerido.bsky.social @shyamalm.bsky.social

Join us this summer for U-M's 2026 #CryoET Data Processing Workshop! This four-day workshop will introduce participants to standard image processing packages and all aspects of cryo-ET data processing. Apply by March 20: myumi.ch/lsi-cryo-workshop-2026 @jbquerido.bsky.social @shyamalm.bsky.social

Hassan Zafar et al.: Breaking barriers: transitioning from X-ray crystallography to cryo-EM for structural studies #CryoElectronMicroscopyCryoEM #StructuralBiology #SingleParticleAnalysis @uvmvermont...#IUCr https://journals.iucr.org/paper?S205979832600080X

This article describes the transition of the Glass laboratory from X-ray crystallography to single-particle cryo-electron microscopy (cryo-EM) for structural studies of ATAD2B, a large AAA+ ATPase- and bromodomain-containing protein involved in chromatin regulation. It outlines practical strategies for protein expression, sample preparation, data processing and model building, offering a comprehensive workflow and troubleshooting guide for new cryo-EM users working with large, flexible macromolecular complexes.

We used the AI-powered tool LabGym to analyze the behavior of Punch 🐒—a Japanese macaque at Ichikawa City Zoo who recently became a social media sensation. (Original video source: @JapanZooStory YouTube Channel) #Punch #PunchTheMonkey #AnimalVideo #labgymbeh @umlifesciences.bsky.social