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The end of a great meeting: Gemma Crupi @magnanilab.bsky.social @icr.ac.uk won the EMBO reports poster prize at #embocancerevolution in Rimini. -> meetings.embo.org/event/26-can... Congratulations!
Attending the GRC conference “Endosomes and Lysosomes in Action Across Cells, Tissues and Disease States” in Andover, NH? www.grc.org/lysosomes-an... Talk to our editor Martina Rembold who is attending the meeting about your work or publishing-related topics! #lysosome #endosome
Congratulations to Mayra Aguirre-Garcia from Annemarie Meijers lab @unileiden.bsky.social for receiving the EMBO reports poster prize at #EMBOpathogenSignalling for her work "GBP1 recruitment to Mycobacteria-containing vesicles through calcium signalling drives #macrophage lysosomal defenses".
Great EMBO YIP @embo.org lecture by Teresa Thurston @thurstonlab.bsky.social @ox.ac.uk at "Pathogen Immunity and Signalling" #EMBOpathogenSignalling. Bacterial effectors mediate kinase reprogramming through mimicry of conserved eukaryotic motifs. See also: -> link.springer.com/article/10.1...
See our first June issue! link.springer.com/journal/4431... The cover features work by Daniel RĂ­os @yosoyden.bsky.social at UNAM in Mexico City and co-workers showing that the #ECM scaffolds interdependent #tissue morphogenesis in #Drosophila. link.springer.com/article/10.1...
Lee Armstrong, Yogesh Kulathu @kulathu.bsky.social and co-workers show that MINDY3's EF-hand domain is a novel #ubiquitin binding domain. It not only enables chain-length-dependent deubiquitination but also binds to DNA repair factors RAD23A/B. -> link.springer.com/article/10.1...
A new review on #evolution is online! Pavithra Venkataraman and Christian Landry @christianlandry.bsky.social discuss a conceptual framework for the joint influence of coding and regulatory mutations in shaping fitness and impacting molecular #evolution. -> link.springer.com/article/10.1...
Attending the EMBO @embo.org workshop "Pathogen Immunity and Signalling" #EMBOpathogenSignalling in Leiden? meetings.embo.org/event/26-pat... Talk to our editor Achim Breiling who is attending the meeting about you work or publishing-related topics!
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A tumour-host feed-forward loop contributes to the growth of chromosomal instability-induced tumours. -> link.springer.com/article/10.1...
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How can funders rethink research excellence with their communities? New @embo.org guest post shares insights from a workshop bringing researchers together to explore fairer, more inclusive assessment aligned with DORA & @coarassessment.bsky.social principles. Explore the full story 👉 bit.ly/RRA-EMBO
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The MINDY family of deubiquitinases (DUBs) are exemplified by their preference for cleaving K48-linked polyubiquitin. MINDY3 is architecturally distinct from other MINDY DUBs as its catalytic domain s...
link.springer.com
Predicting the fitness effects of mutations is central to understanding molecular evolution and interpreting genome sequence data. Such predictions remain challenging due to the inter-dependent roles ...
link.springer.com
The EF-hand domain of MINDY3 is a ubiquitin and RAD23 UBL-binding domain - EMBO Reports
Molecular evolution in light of regulatory-coding epistasis - EMBO Reports
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A new study led by @milanlab.bsky.social's team at  #IRBBarcelona shows that tumours with chromosomal instability can promote their own growth by damaging the surrounding healthy tissues. ➡️ https://shorturl.at/s4xr5 📌 @emboreports.org DOI: 10.1038/s44319-026-00811-7 #IRBScience #CancerResearch
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IRB Barcelona