Adapting the 10x workflow to detect EBV reads, Younis et al show that EBV-transcribing B cells are increased in SLE patients, especially among CD27+CD21low B cells. They have autoreactive BCRs and are more poised for antigen-presentation.
2025 Sci Transl Med ๐งช โ
www.science.org/doi/10.1126/...
Damgaard et al โ 2016 โ The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity in @cellpress.bsky.social
doi.org/10.1016/j.ce...