Today at PI_Forum Brno we will discuss this graph.
From 62% women at PhD level to 17% at professor level.
Let’s talk about why this happens—and how to change it. 📍 CEITEC MU | 🕠 17:30 czexpats.org/en/udalost/p... @czexpats.bsky.social
Author copies of our new book on statistics (mainly) for life scientists arrived recently. After three years of work, this is exciting, especially as we really hope it can help make a positive difference.
What's so special about it?
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Peter Fabian
Excited to share our new study, now out on bioRxiv: www.biorxiv.org/content/10.6...
In this work, we identify CK1α as a novel positive regulator of NOTCH1 signaling and uncover a previously unknown phosphorylation-dependent regulatory mechanism centered on N1ICD residue S1970.
Paper alert! 🤓 Cells talk to one another all the time using cascades of protein interactions. Now, we know for quite some time that proteins from different cascades can interact with each other. It's called crosstalk. But doesn't it defy the logic of clear communication channels between cells? 🧐
By combining cell biology, structural modeling, NMR, mass spectrometry, and Xenopus in vivo assays, we show how CK1α activity supports assembly of the active NOTCH1 transcriptional complex.
