Re-engineering the ribosome to create a fundamentally new form of chemical matter. C-GEM is an NSF Center for Chemical Innovation (CHE-2503885 and 2002182). #NSFfunded
Find us online at www.gem-net.net
C-GEM, the NSF Center for Genetically Encoded Materials
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New paper alert 🚨 from @cgemcci.bsky.social showing high-resolution cryo-EM structures and mass spectrometry data that help us understand how beta-hydroxy acids are accommodated and incorporated by the ribosome!
✨ New preprint from C-GEM: Altering the ribosome exit tunnel to improve consecutive incorporation of challenging monomers
Link: www.biorxiv.org/content/10.6...
This paper is a fantastic collaboration between the Cate and Schepartz labs catalyzed by C-GEM.
#NSFfunded
Out today in Science Magazine — First author Veronika Kivenson and PIs Jill Banfield (The Banfield Lab) and Alanna Schepartz team up to reveal a new genetic code in #archaea, with implications for #methane and #climate, and #bioengineering! Learn more: https://ow.ly/Kuem50Xurh0
Chintan's work demonstrating the efficient incorporation of non-α-amino acid backbones into proteins expressed in both E. coli and mammalian cells just came out! A great collaborative effort from @cgemcci.bsky.social! pubs.acs.org/doi/10.1021/...
C-CAS is now accepting applications for the 2026 Summer Undergraduate Research Fellowship (SURF) Program.
More details here: ccas.nd.edu/outreach/sur...
#chemistry #computerscience #chemsky #summerresearch #REU #undergraduateresearch
🧬 Come visit C-GEM's table to learn about polymer science at the Lawrence Hall of Science's $5 Admission Day on Sunday, May 17, 2026!
Find out more about the event here: lawrencehallofscience.org/events/five-...
✨ New preprint from C-GEM: Bioinformatics-Guided Discovery of a Thermostable and Highly Promiscuous RiPP Cyclodehydratase.
Link: chemrxiv.org/doi/full/10....
This paper is a fantastic collaboration between the Walker, and Schepartz labs catalyzed by C-GEM.
#NSFfunded
✨ Meet this year's cohort of C-GEM Summer Undergraduate Research Program Scholars!
gem-net.net/c-gem-welcom...
#NSFfunded
C-GEM's work was highlighted by APS!
americanpeptidesociety.org/research/rib...
Congrats to @c-majumdar.bsky.social, @alexandra-kent.bsky.social, @nxhamlish.bsky.social, Cathy, Katie, @jhdcate.bsky.social, and Alanna!
Read the original paper in JACS: pubs.acs.org/doi/10.1021/...
#NSFfunded
Today, I'm grateful that Alanna Schepartz is visiting Tufts. Alanna's leadership of @cgemcci.bsky.social has led to impressive advances in genetic code expansion, including recently published work pushing encoding beyond alpha-amino acids.
#ChemSky #ChemChat
www.nature.com/articles/s41...
C-GEM, the NSF Center for Genetically Encoded Materials
Chandrima Majumdar
C-GEM, the NSF Center for Genetically Encoded Materials
Innovative Genomics Institute
C-GEM, the NSF Center for Genetically Encoded Materials
C-GEM, the NSF Center for Genetically Encoded Materials
NSF Center for Computer Assisted Synthesis (C-CAS)
C-GEM, the NSF Center for Genetically Encoded Materials
Abhishek Chatterjee
Ribosomes are capable of incorporating a wide array of natural and unnatural monomers into growing polymer chains, but can be stalled by monomers with constrained or non-natural backbones. Here we eva...
