neuroscience phd student in the Liddelow lab at NYU GSoM | 🏳️🌈
Michael O’Dea
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📄🚨: Building off a stellar 2023 pub that engineered an hCSF1R variant, Sonia et al. now show how an mCSF1R variant not only confers inhibitor resistance and allows for efficient & non-toxic microglia replacement, but does so after vascular delivery into immunocompetent mice! 👏🧠
tinyurl.com/3wvmm8v3
I am proud to share our work on X-linked Dystonia-Parkinsonism — a rare neurodegenerative movement disorder driven by a SINE-VNTR-Alu retrotransposon insertion in the TAF1 gene.
Read our two companion papers:
🔹 www.biorxiv.org/content/10.1...
🔹 www.biorxiv.org/content/10.1...
🧵 Highlights below!
Looking forward to presenting our work on oligodendrocyte dysfunction in a rare neurodegenerative movement disorder X-linked Dystonia Parkinsonism. Come say hi if you're around on Tuesday, Nov 18 between 1-5 pm! @sfn.org #SfN2025 #SfN25
I am excited to share that I will be opening my lab as a tenure-track Assistant Professor in the Department of Pharmacological Sciences at Stony Brook University Renaissance School of Medicine, beginning in March 2027. @stonybrooku.bsky.social @stonybrookmedicine.bsky.social
www.prakash-lab.org
I was featured on The Scientist as a part of their 'Postdoc Portraits' series where I spoke about my scientific career path and ongoing work on oligodendrocyte dysfunction in neurodegeneration. Check it out! www.the-scientist.com/postdoc-port...
#SfN #SocietyForGlia
STARTING NOW!
Ending strong with the last www.liddelowlab.com presentations of the week.
@pryprk.bsky.social
talking about a world first mouse model for XDP... and OLIGODENDROCYTES!
@melcooperphd.bsky.social
presenting on astrocyte networks in the mouse forebrain.
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
Thrilled to share our new publication on the regulatory code of injury responsive enhancers in the CNS!
www.nature.com/articles/s41...
@ellorens.bsky.social
@ki.se
@natneuro.nature.com
Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres!
The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!
Microglia replacement holds great promise for the study and treatment of neurological diseases. We previously achieved high-efficiency replacement by …
tinyurl.com
This postdoc uncovers how glial dysfunction drives neurodegeneration in a rare movement disorder.
Karolinska Institutet är ett av Europas största medicinska universitet. I Sverige har KI det största utbudet av medicinska utbildningar och står för den enskilt största andelen av den medicinska akade...
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
Margherita Zamboni
Melissa Cooper, PhD
Shane Liddelow
Shane Liddelow
Shane Liddelow
Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.
