📄🚨: Building off a stellar 2023 pub that engineered an hCSF1R variant, Sonia et al. now show how an mCSF1R variant not only confers inhibitor resistance and allows for efficient & non-toxic microglia replacement, but does so after vascular delivery into immunocompetent mice! 👏🧠
tinyurl.com/3wvmm8v3
Microglia replacement holds great promise for the study and treatment of neurological diseases. We previously achieved high-efficiency replacement by …
