PhD (Cardiac Physiology) 🧬❤️
Experimentalist 🔬 transitioning to drylab 🖥️
Frustrated runner 🏃 🌱
Chicago, IL
Carlos Henrique Pereira
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This book is essential reading for physical educators. It contains more comprehensive information about women athletes than was available in my entire physical education BA curriculum around 2007. @christineyu.bsky.social
What a week! Full of learning, new ideas, and inspiring conversations. I met so many brilliant and kind people, and I’m leaving with fresh perspectives. Thanks @nitmb.bsky.social
Just finished the Santa Fe Institute course on complexity.
@melaniemitchell.bsky.social Complexity: A Guided Tour once reshaped how I saw science and nudged me from experimental physiology toward modeling. The path hasn’t been easy, but this course and learning NetLogo renewed my motivation.
Multielectrode arrays can be used to investigate electric activity (field potential duration, conduction velocity, arrhythmic substrates, etc.) in cardiac tissue and cells. Useful to investigate the effect of diseases and drugs. 🧪
Experimental recordings alongside my 1st agent-based model (ABM) of calcium transients using @netlogo.bsky.social .
Same experiments I once performed in real cells, now explored through an ABM.
Still refining details, but already happy with the results.
Same biology, just asking new questions.
Calcium imaging in cardiomyocytes is a method used to measure intracellular calcium levels and assess calcium dynamics. It is a powerful tool for investigating the effects of diseases and drugs on cardiac electrophysiology and contraction, providing insights into the mechanisms of arrhythmias.
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Calcium transient imaging using an @ionoptix.bsky.social setup. On the bottom of the screen we can the pretty cardiomyocyte "beating". 🧪
We just published an article exploring how ulcerative colitis, a disease that starts in the gut, can lead to reduced heart contractility
The figure is a summary abstract to illustrate the mechanism we uncovered. If you’re curious click the link for the complete article
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www.mdpi.com/2218-273X/16...
I wish I had discovered NetLogo @netlogo.bsky.social and this wonderful tutorial from Complexity Explorer (SFI @sfiscience.bsky.social) much sooner.
www.complexityexplorer.org/courses/84-f...
Ever wondered about the heart-gut connection in inflammatory bowel disease? Our brand new paper reveals insights into atrial electrophysiology changes during active ulcerative colitis that may explain the higher risk of arrhythmias in IBD patients.
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www.mdpi.com/2218-273X/15...
