Researcher with an interest in pharmacology and cancer metabolism, Group Leader @mrc-lms.bsky.social & CRUK Career Establishment Awardee
Louise Fets
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Congratulations Will Scott and team @mrc-lms.bsky.social on some fantastic work looking at how adipose tissue remodels in obesity and weight loss.
Why do some #cancer cells develop treatment #resistance? The answer may lie in hidden “storage hubs” inside #tumour cells, which create uneven drug exposure across tumours, according to new #research led by @louisefets.bsky.social from 🇬🇧 @mrc-lms.bsky.social.
One of oncology’s biggest challenges is that the same treatment can work well for some patients but fail completely in others.
Advanced imaging of ovarian tumor samples shows that PARP inhibitors can become trapped in lysosomes, creating internal drug reservoirs that may influence treatment resistance and effectiveness. doi.org/hbswwr
Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social
Join us in Belfast for two days of rigorous metabolic science, ECR-led talks and posters, and exciting opportunities for collaboration. The UK Cancer Metabolism Network is a young but fun and open community - do check out the meeting, registration open until 24th March!
Seconded! Worth a look for anyone who wants to open a lab working on metabolic physiology and/or disease, or immunometabolism
Great collaboration that took us to places we definitely were not anticipating! Thank you Zoe and congratulations to you too! 🎉 ♥️
Louise Fets
Louise Fets
Vicki Metzis
Science X / Phys.org
A new study, published today in Nature, reveals the hidden benefits of weight loss on fat tissue.
A better understanding of how weight loss leads to health improvements at a molecular level could help inform the development of therapies for diseases such as type 2 diabetes in the future.
Excellent opportunity @mrc-lms.bsky.social for a human physiologist to start their own group. Deadline 4th May.
Core funding, excellent package.
Please repost!
lms.mrc.ac.uk/work/vacanci...
Congrats to the drug transport and tumour metabolism group, headed by @louisefets.bsky.social for winning two awards!
Scientists from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have produced the first detailed characterisation of the changes that weight loss causes in human fat tissue by...
We're recruiting junior team leaders @mrc-lms.bsky.social This time we're looking for those working in human metabolic disease.
It's a great place to start your lab. Fantastic colleagues, exciting science, world class facilities. Join us!
lms.mrc.ac.uk/work/vacanci...
MRC Laboratory of Medical Sciences
MRC Laboratory of Medical Sciences
We are recruiting Programme Leader Track positions focusing on 1) Metabolic Physiology using murine and/or human in vivo models and 2) Immunometabolism.
In our new paper with @louisefets.bsky.social we show with #MSI that drugs can accumulate heterogeneously in #ovarian #cancer and may explain why treatments work well in some patients and not others. Huge congrats to Carmen Ramirez Moncayo, Louise and all authors! bit.ly/4byaY9W
Cancer drugs can accumulate in hidden “storage hubs” inside tumour cells, creating uneven drug exposure across tumours, according to new...
