In our study in @natcomms.nature.com we used #EPR #DEER #PELDOR spectroscopy with single subunit heterologous spin labelling and monitored the entire cap conformational ensemble of the human mechanosensitive TRAAK channel and showed it adopts two states in membranes.
www.nature.com/articles/s41...
âš New paper out in #JACS! We looked at the intrinsically disordered CTD tail of #Hsp90 often seen as a passive linker. Turns out, itâs not.
#StructuralBiology #Biophysics #EPR #NMR
pubs.acs.org/doi/10.1021/...
Our #openaccess work shows that P. fluorescens #Esterase is robust in crowded media and most divalent metals. But CuÂČâș and ZnÂČâș inhibit activity through aggregation. Insights into enzyme behavior in complex environments.
đ doi.org/10.1002/cbic...
#Biocatalysis #Enzymology
Proteinâpolymer conjugates: how do we understand their structure & dynamics? đŹOur new review highlights EPR spectroscopy+complementary techniques for insights in vitro & in cells.
Read more đ
www.sciencedirect.com/science/arti...
#ProteinPolymerConjugates #EPR #Biomaterials #PolymerScience
Just published: copper(II) binding to Human Serum Albumin. 1st structure including the ATCUN site that is square planar as expected. There are multiple copper(II) sites and EPR (including hyperfine and pulse dipolar) reveals occupation of multiple sites at low loading. doi.org/10.1039/D6QI...
Wouldn't it be great if REF and ResearchFish disappeared off into the sunset together?
Scrapping REF should be âseriousâ option, says Manchester VC www.researchprofessionalnews.com/rr-news-uk-u...
Pliotas Group
Angeliki Giannouli
Angeliki Giannouli
Angeliki Giannouli
Work just published in @natcomms.nature.com rdcu.be/e9ieD demonstrating how pulse dipolar EPR can resolve different states of a human transporter in native membranes. EPR contributions by @ackermannkatrin.bsky.social @st-andrewschem.bsky.social
Great work by Aisika, @ackermannkatrin.bsky.social at
@st-andrewschem.bsky.social #chemsky đ§Ș
Just published đ: Binding Affinity Determines the Success of Endogenous CuII-NTA Spin Labeling for In-Cell Electron Paramagnetic Resonance Distance Measurements | The Journal of Physical Chemistry Letters @pubs.acs.org @ackermannkatrin.bsky.social pubs.acs.org/doi/10.1021/... #chemsky đ§Ș
Bela Bode
Bela Bode
Bela Bode
Bela Bode
Malcolm White
Great collaboration with @pliotasgroup.bsky.social and @yuemauom.bsky.social
