Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf
Una investigación internacional liderada desde el IN CSIC-UMH rastrea a lo largo de la evolución las proteínas que nos permiten identificar las bajas temperaturas ❄️
Lo explica @neuroviana.bsky.social para @elconfidencial.bsky.social 👇
www.elconfidencial.com/tecnologia/c...
@painchannels.bsky.social
This Friday we had the privilege of hosting Dr. Wenqin Luo at
@neuroalc.bsky.social. It was great to learn about the transcriptional profiling of human DRG & TG neurons 🙏 Dr. Ana Gomis @painchannels.bsky.social
for organizing. Very interesting discussions afterwards.
#pain #transcriptomics #itch
Una investigación internacional rastrea a lo largo de la evolución las proteínas que nos permiten identificar las bajas temperaturas
I am glad to share our recent work, now published in Cell! A @zenbrainest.bsky.social and Scherrer lab collaboration developing and validating a new peripherally restricted DREADD system! Great team work with Hye Jin Kang, Brian Krumm, @adrtas.bsky.social, and others
www.cell.com/cell/abstrac...
New blogpost:
deevybee.blogspot.com/2024/11/why-...
findaphd.com
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Kang et al. present HCAD, a peripherally restricted DREADD based on HCA2, with a chemical actuator that avoids crossing the blood-brain barrier and selectively reduces pain in mice. This system will enable the study of peripheral physiology without affecting the central nervous system.
Hello everyone. We are flying away from the toxic X
The @painchannels.bsky.social group @neuroalc.bsky.social is having a good time this morning. My little white feathered wings are still very small and I can hide them under my shirt 🐙🐙
Marina Vilaró, flying over all of us is our artist in residence
Such a nice, comprehensive review by @marcvoo.bsky.social and @erin-schuman.bsky.social on the molecular diversity of synapses (h/t @djabaudon.bsky.social):
www.nature.com/articles/s41...
Painchannels
www.nature.com
The set of proteins present at synapses determines their heterogeneous functions and properties. In this Review, van Oostrum and Schuman describe the molecular mechanisms that contribute to the d...