New version of OrfM, a simple and not slow open reading frame (ORF) caller, is out. Still simple, but a port from C to Rust gained ~25% on runtime. Now with an API too. github.com/wwood/OrfM
Our study describing `microntology` and annotations for >300k metagenomes is now online in Bioinformatics @academic.oup.com :
academic.oup.com/bioinformati...
Congratulations to @fullam.bsky.social @vishnuprasoodanan.bsky.social & @biocs.bsky.social !
See the thread below for more details.
This is awful to hear, describing how Sean Eddy (HMMER, infernal, pfam, rfam) has been defunded. The letter said his work
"had been determined to be of absolutely no value to the US taxpayer, and therefore it was being specifically terminated,"
www.npr.org/2026/05/21/n...
We now provide environmental metadata for the GlobDB genomes!
🖥️🧬🦠
More info here:
globdb.org/news
🧵
Today marks 30 years since we identified the apicoplast, a relict plastid in human and animal parasites (PMID 8632819). Apicoplasts are the target of the widely used antimalarial prophylactic doxycycline, which has saved many thousands of malaria infections.
We’re excited to announce our keynote speakers for the JAMS 15 Symposium – Brisbane 2026! 🧬✨
This year, JAMS 15 will feature an incredible lineup of researchers and leaders in microbiology, infectious diseases, and antimicrobial resistance research.
SingleM 0.21 is go - @ace-gtdb.bsky.social R232 reference database, less verbose logging, fixes, etc. Thanks @thepatientwait.bsky.social @aroneys.bsky.social @rossenzhao.bsky.social and on GitHun @EisenRa @magicprotoss @MCeciC
GTDB release 11 based on RefSeq 232 (R11-RS232) is live at gtdb.ecogenomic.org. This release covers 901,341 genomes (23% increase) and has 199,923 species clusters (39% increase). Release notes at: forum.gtdb.ecogenomic.org/t/announcing.... Release statistics at: gtdb.ecogenomic.org/stats/r232.
Sandpiper 2 is up. 913,000 metagenomic community profiles w @ace-gtdb.bsky.social R232, 200k more than 1.0. sandpiper.qut.edu.au
GlobDB coming.
Thanks to @aroneys.bsky.social @thepatientwait.bsky.social @iambrettb.bsky.social and especially the new kid @nhstefan.bsky.social