Beyond proteins and DNA, #lipids are emerging as key players in nuclear biology - shaping nuclear envelope dynamics, mechanosensing, gene regulation and genome stability.
Our new Perspective highlights recent advances, open questions, and future directions 👉 journals.biologists.com/jcs/article/...
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature.
Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis.
doi.org/10.1038/s415...
journals.biologists.com
Summary: Lipids are increasingly recognized as essential regulators of nuclear homeostasis, membrane dynamics, mechanotransduction and genome stability, opening new frontiers for understanding nuclear...
We’re also very grateful to The Company of Biologists @biologists.bsky.social for supporting these workshops and bringing scientists together & to Gautam Dey @gautamdey.bsky.social for kindly sharing information about them.
This Perspective emerged from scientific discussions at a Company of Biologists Workshop @biologists.bsky.social organised by María Moriel-Carretero @morieLAB.bsky.social & Aurélia E. Lewis. They sparked the idea for this Perspective and helped review the drafts. Many thanks to both!
Finally, we are thrilled that our work will be part of the Journal of Cell Science @jcellsci.bsky.social special issue on ‘Cell Biology of the Nucleus’!
Marintia Nava-García
Marintia Nava-García
Marintia Nava-García
What membrane properties do cells maintain through regulation of lipid metabolism? In a new paper, we identify intrinsic curvature stress as one such parameter and show how different (eukaryotic) cell types employ different lipids to do that www.cell.com/cell-reports...
Excited to share the first study from the Morstein Lab on a new approach that enables selective editing, tagging, and visualization of mammalian lipids
www.biorxiv.org/cgi/content/...
#chembio #lipidtime @caltech.edu @caltechcce.bsky.social @harayamajrlab.bsky.social @logan-tenney.bsky.social
Itay Budin
Happy to share the final version of this work is now out in @natchembio.nature.com. Lots of additional exciting data! Congrats to all the authors!
Johannes Morstein
Science really takes a village. Thrilled to share this with my friend @dudinlab.bsky.social, and with our brilliant and fearless teams, our collaborators around the world and our mentors - in my case a special shoutout to Buzz Baum, Jan Ellenberg and @monicabettencourt.bsky.social.
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☄️New biosensor!☄️ We present Meteor, our GFP-based methionine optical reporter, which can be used to measure methionine dynamics across scales, from subcellular to organisms like C elegans! Plasmids will be deposited with Addgene. www.biorxiv.org/content/10.6...
Congratulations to Gautam Dey (EMBL) and Omaya Dudin (University of Geneva) for being awarded the EMBO Gold Medal 2026 in recognition of their outstanding contributions to the #LifeSciences in Europe! 🧪 https://www.embo.org/press-releases/embo-gold-medal-2026-awarded-to-gautam-dey-and-omaya-dudin/
Chris Parker
Schmitt Lab @ UCLA
EMBO
Gautam Dey
Cells maintain membrane function by actively balancing the molecular shape of their
lipids. Milshteyn et al. find that, when subjected to high hydrostatic pressure, yeast
and human cells, but not bact...
