Our paper is now out in @natcellbio.nature.com! @craigmcrews.bsky.social
www.nature.com/articles/s41...
We identify a new regulator of the quality control system that protects one of nature's most important molecular machines: the ribosome. QC failure → unmitigated metabolic stress & cell death.
Todd Douglas
No wonder it’s complicated to understand immune responses. We are part bacteria part virus too, more than we thought!
Congrats superToni and Gabaldón lab
Register to receive it by email at eepurl.com/cvQCw9
The “ERC cliff”
My opinion about the distribution of European Research Council funding per age (experience) group
www.timeshighereducation.com/opinion/erc-...
Cell death and immune responses are linked all across the tree of life. But they interact in funny and opposing ways depending on the species
"FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster"
link.springer.com/article/10.1...
Lots of papers on cell death (and even senescence) this month!
- Bcl-XL inhibition targets neutrophils
- caspase-3 activation by non-canonical inflammasomes
- ferroptosis is immunosuppressive in cancer models (@lyssiotislab.bsky.social)
and much more! ApoList
celldeath.wordpress.com/2026/06/04/a...
Not even a podium this tall can contain the energy and talent of Jessalyn Ubellacker
@ubellackerlab.bsky.social @met-hsph.bsky.social
She can make ferroptosis sounds interesting 😂
Cristina Muñoz Pinedo
📢 Upcoming Seminar | Don't miss our plenary #seminar this Friday, with Dr. Daniel Muñoz-Espin, from the Early Cancer Institute (ECI),
@cam.ac.uk.
🤝 Hosted by @milanlab.bsky.social & @direnaac.bsky.social.
Register here ➡️ https://shorturl.at/klN05
#IRBBarcelona #AgeingResearch #AgingResearch
Cristina Muñoz Pinedo
Cancer metabolism, inmunometabolism,
Mitochondria, metabolic stress, cancer cachexia, hypoxia and more
Metabolist May 2026
metabolist.wordpress.com/2026/06/08/m...
"...resign themselves to the “normal” condition of a scientist in Europe: broke and anxious."
So true, sadly.
Cristina Muñoz Pinedo
Cristina Muñoz Pinedo
Cristina Muñoz Pinedo
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature.
Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis.
doi.org/10.1038/s415...
Cristina Muñoz Pinedo
IRB Barcelona
Cristina Muñoz Pinedo
Toni Gabaldón
Douglas et al. study the E3 ligase HOIL-1, mutated in patients with a type of myopathy. Mutant HOIL-1 influences the sensitivity to disulfidptosis initiated by ZAKα–ATF4 in glucose starvation and inte...
STING is an evolutionarily conserved key regulator of innate immunity. In the model organism Drosophila melanogaster, STING activates the NF-κB-like transcription factor Relish, initially characterize...
Bcl-2 family proteins Pseudo-senescence induced by palbociclib does not sensitise pleural mesothelioma cells to combinations with senolytics Iswarya Sreeram, Sílvia Plans-Marin, Mabel Cruz-Rodrígue…
