Want to map protein-RNA interactions? Check out our new iCLIP3 protocol. Featuring steamlined library prep and visualisation of protein-RNA complexes without radioactivity! Bioinformatics workflow on top :)
With the Müller-McNicoll and Zarnack labs!
@zarnack-group.bsky.social @mixmue.bsky.social
For 40 years the 8-nt ‘Kozak Sequence’ was thought to mark sites of translation initiation. In a new study, we revise this model by identifying an ~80-nt sequence—the extended Translation Initiation Sequence (eTIS)— that guides ribosomes to correct start sites. 🧵
www.biorxiv.org/content/10.6...
Chromosomen, DNA, Sex und Stille Bedrohungen für unsere Spezies🧬👩🏼🔬👨🔬
Alles dies bei der #pint26de Veranstaltung am 18. Mai
📍Aposto 🕤18 Uhr
Komm vorbei und lernt Annika und @reneketting.bsky.social kennen!
Karten🎟👉 www.pintofscience.de/events/mainz
@imbmainz.bsky.social @unimainz.bsky.social
New paper in Genes & Dev: we dissected how Sox2 — a key pluripotency TF — is regulated by a distal enhancer cluster (SCR) 100 kb away. The results challenge simple models of cohesin-mediated loop extrusion of gene regulation. genesdev.cshlp.org/content/earl... 🧵
Germ cells have their own versions of core transcription factors and fertility depends on them.
We're hiring a PhD student to figure out how! 📢
Fly genetics + proteomics + genomics. Fully funded.
Aarhus University 🇩🇰
Deadline May 1 👇
Please share with anyone who might be interested!
Thank you @impvienna.bsky.social for featuring our next career step! The support that Ulrich @hohmannulrich.bsky.social and I received from our postdoc labs (@pauligroup.bsky.social, @juliusbrennecke.bsky.social and @plaschkalab.bsky.social), and now from @imbmainz.bsky.social has been key!
Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the thread👇 for the highlights of our findings.
Ulrich’s research will help advance our understanding of RNA biology & gene regulation, as well as how these mechanisms might be altered during viral infections & other diseases.
@hohmannulrich.bsky.social comes from the @impvienna.bsky.social / @imbavienna.bsky.social
www.imb.de/about-imb/ne...
How does the piRNA pathway solve the self vs. non-self problem? 🧬
Since piRNAs come from single-stranded RNA, how does the cell choose the right ones? For years, "piRNA clusters" were seen as THE privileged source. But are they really special and earmarked for biogenesis? (1/19)
@lorenzoorts.bsky.social previously worked as a postdoctoral fellow at @impvienna.bsky.social in Austria. She will establish a new lab at IMB to investigate how mRNA translation is activated in the early embryo. Welcome to IMB Laura! 💐
Read more here: www.imb.de/about-imb/ne...
www.biorxiv.org
Elzo de Wit lab @ NKI
König Lab
ChiaraG
Marvin Tanenbaum
Peter Andersen
phd.nat.au.dk
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
Securing two group leader positions at the same institute is no small feat.
From IMP postdocs to group leaders: Laura Lorenzo-Orts and Ulrich Hohmann started their labs at IMB Mainz this year:
