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Adult neurogenesis: New neurons, new opportunities
Huntington’s disease is the best investment in neuroscience today www.sciencedirect.com/science/arti... #Huntingtons #Neuroscience #Investment
3mo
3mo
Looking forward to trying this out!!
Huntington’s disease (HD) is usually described as rare, tragic, and intractable. Yet, HD offers a strategically unique entry point for neuroscience. W…
www.sciencedirect.com
2mo
dlvr.it
Kempermann and colleagues discuss new directions in neuroscience stemming from an understanding that adult neurogenesis contributes to brain function in health and disease. They discuss the role and function of adult stem cells; the impact of environmental regulation; the interplay between development, plasticity, and aging; and other fundamental questions.
Huntington’s disease is the best investment in neuroscience today
Adult neurogenesis: New neurons, new opportunities
Poul Sørensen
Cell Stem Cell
#MSCA success rates now below 10%, yet the work that goes into writing this application is immense. Beyond the obvious increase in funding we need to find ways to lighten the time investment as well. Thousands of researchers spend weeks if not months working on this.
For obvious reasons, I've become fascinated with retrotransposons. So we ( @alexwhiteley.bsky.social and I) wrote an article now out in Neuron @cellpress.bsky.social on how we think retrotransposons influence brain function and health! kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
4mo
7mo
Excited to share that my main PhD work with @labsalta.bsky.social is now out in @cp-cellstemcell.bsky.social ✨ — with lots of new additions! Feeling very grateful for all the teamwork and everyone who contributed along the way 💜 www.cell.com/cell-stem-ce...
1mo
Giorgia Tosoni
Giorgia Tosoni
www.cell.com
Tosoni and colleagues identify immature neurons in the aged human hippocampus with signatures of younger biological age and cellular fitness. Their molecular programs and intercellular interactions ar...
Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer’s pathology and cognitive resilience
🧵 1/ Excited to share our new research on immature neurons (ImN) in the adult human brain and their roles in healthy aging, Alzheimer’s disease (AD), and cognitive resilience. Here’s what we discovered 👇
Jan 10, 2025
Tahnée Engelen
Jason Shepherd
Giorgia Tosoni
New preprint! Our workflow for processing single cell and nuclei data, called 🎉 scprocess 🎉 We have been working on it for ~18 months now, over which time we have processed at least 2k samples with it, so it has had a decent amount of testing.
3mo
Let's look at some numbers 2022: 7 044 applications submitted. 17.9 % success rate 2023: 8 039 applications submitted. 15.8 % success rate 2024: 10 360 applications submitted. 16.6 % success rate 2025: 17 058 applications submitted (record high). 9.7% success rate (preliminary numbers).