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@ewarman.bsky.social has followed up on her discovery of bidirectional promoters in bacteria by defining their basic rules for regulation and links to gene expression noise... academic.oup.com/nar/article/...
Our lab is offering 3 PhD projects this year across 3 different topics: antibiotic resistance mechanisms, evolution of pathogenic bacteria, and fundamental mechanisms of gene regulation. www.findaphd.com/phds/?Keywor...
'We show that the VqmAj homologs can indeed detect (host autoinducer) DPO and, in response, activate the lytic pathway. Our observation indicates that jVP882 is a member of a large family of globally-dispersed quorum-sensing-responsive temperate phages.' www.biorxiv.org/content/10.1...
📢 Dear lovers of prokaryotic chromosomes: Registration for the Biology & Physics of Chromosomes meeting has been extended until 7 August ⏳. Join us! @biophychrom.bsky.social @danielabarilla.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social #microsky
10mo
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8mo
10mo
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in grainger birmingham. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
www.findaphd.com
Abstract. In prokaryotes, bidirectional promoters are pseudo-symmetrical DNA sequences that stimulate divergent transcription. Ubiquitous, and far more lik
academic.oup.com
grainger birmingham PhD Projects, Programmes & Scholarships - 3 PhDs Listed
A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species
Bidirectional promoters in Escherichia coli: regulatory rules and implications for gene expression noise
Temperate phages oscillate between lysogeny, a genomic maintenance state within a bacterial host, and lytic replication, in which the host is killed, and newly made phage particles are released. Succe...
www.biorxiv.org
Vicky Lioy
Thiago Carvalho
Grainger Lab
Grainger Lab
How are bacterial transport machineries regulated by external cues? @brochadolab.bsky.social &co identify environmental chemicals that regulate #transporter transcription, identifying the TF Rob as a key modulator of #EffluxPump expression in #Ecoli #AMR @plosbiology.org 🧪 plos.io/46pUM9Q
10mo
Two post-doctoral positions open in our lab. We're looking for people with expertise in molecular microbiology and/or genome-scale tools. Initially 3 yrs, posts could be extended for upto 8 yrs. If you'd like to know more about us take a look at www.graingerlab.com www.jobs.ac.uk/job/DQY475/r...
2mo
PLOS Biology
Explore an exciting academic career as a Research Fellow (Postdoctoral). Don't miss out on other academic jobs. Click to apply and explore more opportunities.
Research Fellow (Postdoctoral) at University of Birmingham
www.jobs.ac.uk
Grainger Lab
@danielabarilla.bsky.social kicking off #BioPhyChrom2025 - a fantastic turn out too...
8mo
A busy few weeks for the lab 🥵... three new stories published. The first describes activation of transcription by DNA distortion academic.oup.com/nar/article/...
In our most recent work David Forrest has discovered a widespread mechanisms linking transcription initiation to DNA supercoiling... www.nature.com/articles/s41...
4mo
4mo
Grainger Lab
Abstract. Bacterial RNA polymerase binds and unwinds promoter DNA to initiate transcription. The process is often inefficient and can be stimulated by acti
academic.oup.com
Activation of bacterial transcription by distortion of promoter base pairing
Grainger Lab
www.nature.com
The transcription factor CarD facilitates the activation of transcription in many bacteria and in Rhodobacter sphaeroides, CarD compensates for suboptimal promoter DNA sequences. Here, the authors sho...
The bacterial RNA polymerase-associated CarD protein couples promoter activity to DNA supercoiling - Nature Communications
Grainger Lab
Talk slots full but we can take late breaking poster abstracts until August 7th. Hope to see you in York to hear about your chromosome story 🧬🦠🧫 www.eventsforce.net/biochemsoc/f... @vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social
10mo
Grainger Lab