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Group Leader of Computational Immunogenomics group at VHIO | Data Mining lead at HartwigMedicalFoundation | Personal account | Advocate for social and environmental justice 🌍 https://www.franmartinezlab.com/
Fran Martínez-Jiménez








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Monthly median Received to Accepted time (days) at Nature Genetics
Why should tumor whole genome sequencing (WGS) be done for cancer? In real practice of medicine study of 888 patients with solid cancers, WGS directly led to clinical consequences in over 40% www.nature.com/articles/s41...
‼️Last days to apply for our postdoc position in the group! Please share!! jobs.vhio.net/en/jobs/7256...
Here's a short guide to good practices for #8M, that we've prepared from the Equality Commission of @vhio.bsky.social.
Excited to share our ‘Evolutionary characterization of lung cancer metastasis’ in #TRACERx & #PEACE, published today in @nature.com in collaboration with @charlesswanton.bsky.social @nickymcgranahan.bsky.social @zaccasimo.bsky.social at @ucl.ac.uk & @crick.ac.uk. www.nature.com/articles/s41...
Excited to share our latest work in Nature. Applying single-molecule and single-cell DNA sequencing methods, we uncover an extraordinary landscape of somatic mutations in immune checkpoint genes in autoimmune B cells, suggesting that somatic mutations may be key to autoimmunity [1/n] rdcu.be/fdqbr
Today in @science.org: We are pleased to present our last work entitled: "Concurrent L1 retrotransposition events promote reciprocal translocations in human tumorigenesis" by Zumalave et al. www.science.org/doi/10.1126/...
Tumor promotion through the lens of evolution This review grew out of many long conversations, shared ideas, and lively discussions It has been a real pleasure to think together with Allan, Paul, Eve, and Abel about how tumours develop and how carcinogens shape cancer risk rdcu.be/fdC2J
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📣 Are you an #MD passionate about research?  Fundació Catalunya La Pedrera #VHIO MD-PhD Fellowship is now open! 🚀 An excellent opportunity for MDs who wish to become experts in translational medicine 👉 https://linke.to/FellowshipPedreraVHIO2026 📅 Deadline: May 14th @cerca.cat
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DNA-sequencing data from primary tumours and paired metastases from participants in the TRACERx lung study and PEACE autopsy programme are used to analyse the metastatic diversity of advanced non-smal...
www.nature.com
Evolutionary characterization of lung cancer metastasis - Nature
1mo
Nature - Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity
Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity
rdcu.be
Tumour promotion through the lens of evolution
Nature - This Review revisits tumour initiation and promotion in light of clonal diversity and the presence of cancer driver mutations in normal tissues, aiming to understand mechanisms that enable...
rdcu.be
Fran Martínez-Jiménez
In a real-world cohort of 888 patients with solid cancers receiving whole-genome sequencing profiling, actionable biomarkers were identified in 73% of patients, and targeted therapies were associated ...
www.nature.com
Real-world clinical utility of tumor whole-genome sequencing in solid cancers - Nature Medicine
Sasha Gusev
Eric Topol
Ana Dueso-Barroso
Under the leadership of Josep Tabernero, VHIO is an internationally recognized cancer center. Its multidisciplinary, collaborative model drives scientific progress and innovative cancer treatments.
jobs.vhio.net
LINE-1 (L1) retrotransposition generates somatic genomic variation in human cancer, but short-read sequencing has limited our understanding of its structural consequences and dynamics. Using long-read...
2026-018-01 Postdoctoral fellow in cancer immunogenomics - VHIO
Concurrent L1 retrotransposition events promote reciprocal translocations in human tumorigenesis
www.science.org
Jamal-Hanjani Lab
Inigo Martincorena
Jose Tubio’s lab - Mobile Genomes
Nuria Lopez-Bigas
Vall d’Hebron Institute of Oncology