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Today in @science.org: We are pleased to present our last work entitled: "Concurrent L1 retrotransposition events promote reciprocal translocations in human tumorigenesis" by Zumalave et al. www.science.org/doi/10.1126/...
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www.science.org
LINE-1 (L1) retrotransposition generates somatic genomic variation in human cancer, but short-read sequencing has limited our understanding of its structural consequences and dynamics. Using long-read...
Concurrent L1 retrotransposition events promote reciprocal translocations in human tumorigenesis
Jose Tubio’s lab - Mobile Genomes