postdoctoral researcher at the MPI for biological intelligence I development & evolution of the brain I interactions of transcription factors
Elena Dvoretskova
New preprint from our lab on bioRxiv: “Stoichiometric transcription factor partnerships control GABAergic neuron fate allocation”
www.biorxiv.org/content/10.6...
A great collaboration with @annrosebright.bsky.social, Connor Lynch, @chr-mayer.bsky.social, and many others.
Very nicely done Radiolab episode featuring @emilyjacobs.bsky.social and team’s work. Check it out! radiolab.org/podcast/this...
#Science #Biologie
🦇 « L’évolution des mécanismes du développement »
🖥️ Les vidéos du colloque organisé par le Pr @denisduboule.bsky.social, titulaire de la chaire #Évolution du développement et des #génomes, sont disponibles !
👉 https://tinyurl.com/39p4h5pn
Sun et al, 2026. NuRD-enabled CTCF-TET crosstalk orchestrates epigenome reprogramming and genome architecture www.cell.com/molecular-ce...
🧬 🧪Our RNA velocity benchmark is out in PLOS Comp Biol
We tested 5 methods on mouse & zebrafish data. They often disagree (just 1/100 driver genes shared 😬). A hypothesis tool, not ground truth.
Open access 👉 doi.org/10.1371/jour...
Led by the brilliant Sarah Ancheta (not on bsky)
Single Cell Genomics Day: A (Virtual) Practical Workshop.
June 12, 2026, organized by @nygenome.org's Rahul Satija
Free, livestreamed, no registration.
Exciting breakthrough technology from the lab, now live in
@cellcellpress.bsky.social
! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!
(1/n) Very excited to share tri-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack:
Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)?
A: Transient E-P contact (~25-42 nm lasting ~10-20 sec):
www.biorxiv.org/content/10.6...
Researchers recorded from single neurons across frontotemporal cortex in 8 awake individuals during natural speech. They show how activities of collections of cells can capture syntactic & semantic properties of words, & also dynamically incorporate sentence context to encode combinatorial info.
🗣️🧠🧪
Bumble bees can apparently play with balls, count, recognize faces, & perceive rhythm. A new study out today in @science.org argues they can also solve novel tasks spontaneously without explicit training, challenging the idea that such cognitive skills are exclusive to large-brained vertebrates.😲🐝🧪👇
Video
Combinatorial transcription factor (TF) codes specify neuronal fates, yet how quantitative differences in interacting TFs shape these decisions remains unresolved. We address this in the developing ba...
Problem-solving using novel solutions without explicit training is often considered a hallmark of cognitive flexibility. We investigated whether bumble bees (Bombus terrestris) could solve a novel obj...
Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the...
