Ear Bending: Atlas of genes active in single cells of the developing inner ear
📷 @akankshi.bsky.social & @kkukreja.bsky.social et al @swinburnelab.bsky.social @harvardmed.bsky.social in
@elife.bsky.social
➡️ bpod.org.uk/archive/2026...
Intrinsically disordered proteins (IDPs) flit between diverse shapes and interact in fuzzy ensembles whose collective properties shape function.
Q: Can we rationally design emergent properties of IDPs?
Our newest preprint takes a stab at this 🧵
biorxiv.org/content/10.6...
🥁We are recruiting PhD students/Postdocs with strong proven background in developmental/molecular/cell biology & related areas, for various projects- check out our lab website👇🏼
We offer: competitive stipends, super equipped lab, fun international team!
yanivelkoubylab.com
Thank you so much @amjeve.bsky.social , @biologists.bsky.social and @dev-journal.bsky.social for the opportunity and for all the help with the piece.
(3/3)
This is my 1st publication with Development & it was such a pleasure. Nt only did reviewers provide v. constructive comments, the Editor himself (Alex Eve) also read the paper carefully & gave us very useful suggestions to improve the readability of this piece.
(2/3)
Happy to share our latest in @natcomputsci.nature.com
led by (amazing) Ryan Krueger + colab w M. Brenner!
We introduce a framework to directly design intrinsically disordered proteins (IDPs) from physics-based simulations.
🧬 doi.org/10.1038/s435...
📰 www.mccormick.northwestern.edu/news/article...
Our review on cell cycle – cell fate (de)coupling is out! doi.org/10.1242/dev....
Was a lot of fun writing this with Allon Klein, reading old papers(earliest from 1902), and speculating on why cell cycle progression is not necessary for differentiation across many many tissues and species.
(1/3)
Coupling and decoupling of the cell cycle from cell differentiation in development
In this Spotlight, @kkukreja.bsky.social & Allon Klein discuss the dependence of animal cell differentiation on cell cycle, and how their decoupling facilitates development
journals.biologists.com/dev/article-...
just finished reading katalin kariko
@kkariko.bsky.social 's memoir. easily one of the most inspiring books I have read. whenever I feel down at work, face rejections or things feel unfair and hard, I can just hug the book to sleep and remind myself why we do science . . . .
📢 @shrinivaslab.bsky.social and colleagues introduce a method for designing unstructured proteins with tunable properties. www.nature.com/articles/s43... 🖥️ 🧬
🔓 rdcu.be/eJSuV